{"doi":"10.1007/s10552-024-01849-5","title":"Traditional Mexican dietary pattern and cancer risk among women of Mexican descent","abstract":"PURPOSE: To examine the association of a traditional Mexican diet score with risk of total, breast, and colorectal cancer among women of Mexican ethnic descent in the Women's Health Initiative (WHI). METHODS: Participants were WHI enrollees who self-identified as being of Mexican descent. Data from food frequency questionnaires self-administered at study baseline were used to calculate the MexD score, with higher scores indicating greater adherence to an a priori-defined traditional Mexican diet (high in dietary fiber, vegetables, and legumes). Incident cancers were self-reported by participants from 1993 to 2020 and adjudicated by trained physicians. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: Among 2,343 Mexican descent women (median baseline age: 59 years), a total of 270 cancers (88 breast, 37 colorectal) occurred during a mean follow-up of 14.4 years. The highest tertile of MexD score was associated with a lower risk of all-cancer incidence (HR: 0.67; 95% CI 0.49-0.91; p-trend: 0.01) and colorectal cancer (HR: 0.38; 95% CI 0.14-0.998; p-trend < 0.05), with each unit increase in the MexD score associated with a 6% lower risk of all-cancer incidence (HR: 0.94; 95% CI 0.88-0.99). There was no statistically significant association with risk of breast cancer. CONCLUSION: Consumption of a traditional Mexican diet was associated with a significantly lower risk of all-cancer incidence and colorectal cancer. Confirmation of these findings in future studies is important, given the prevalence of colorectal cancer and a growing U.S. population of women of Mexican descent.","journal":"Cancer Causes & Control","year":2024,"id":448274,"datarank":0.26876392038420827,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.0,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.913,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":564651,"name":"Margarita Santiago‐Torres","orcid":"0000-0001-6051-3172","position":1,"is_corresponding":false},{"id":921856,"name":"Melissa Lopez‐Pentecost","orcid":"0000-0002-7048-3699","position":2,"is_corresponding":false},{"id":383464,"name":"Lorena García","orcid":"0000-0002-9976-761X","position":3,"is_corresponding":false},{"id":272433,"name":"Aladdin H. Shadyab","orcid":"0000-0002-9693-0522","position":4,"is_corresponding":false},{"id":245942,"name":"Yangbo Sun","orcid":"0000-0003-0377-4450","position":5,"is_corresponding":false},{"id":390224,"name":"Candyce H. Kroenke","orcid":"0000-0002-6128-3118","position":6,"is_corresponding":false},{"id":243123,"name":"Linda Snetselaar","orcid":"0000-0002-6615-0779","position":7,"is_corresponding":false},{"id":75616,"name":"Marcia L. Stefanick","orcid":"0000-0002-0284-6996","position":8,"is_corresponding":false},{"id":27761,"name":"Marian L. Neuhouser","orcid":"0000-0002-3876-0000","position":9,"is_corresponding":false},{"id":1087524,"name":"Nicole C. Loroña","orcid":"0000-0002-8302-3157","position":0,"is_corresponding":true}],"reference_count":41,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:02:08.018689Z","pmid":"38305935","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}