{"doi":"10.1007/s00787-006-0547-2","title":"Impaired working speed and executive functions as frontal lobe dysfunctions in young first-degree relatives of schizophrenic patients","abstract":null,"journal":"European Child & Adolescent Psychiatry","year":2006,"id":685502,"datarank":0.519860385419959,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.0,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1790967,"name":"Beate Schmidt","orcid":null,"position":1,"is_corresponding":false},{"id":1790968,"name":"Susanne Knappe","orcid":null,"position":2,"is_corresponding":false},{"id":1790969,"name":"Bernhard Blanz","orcid":null,"position":3,"is_corresponding":false},{"id":1790966,"name":"Silke Klemm","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Impaired working speed and executive functions as frontal lobe dysfunctions in young first-degree relatives of schizophrenic patients","abstract":"The aim of the investigation was to detect neuropsychological markers, such as sustained and selective attention and executive functions, which contribute to the vulnerability to schizophrenia especially in young persons. Performance was assessed in 32 siblings and children of schizophrenic patients and 32 matched controls using Wisconsin Card Sorting Test, Colour-Word-Interference-Test, Trail Making Test, and d2-Concentration-Test. The first-degree relatives showed certain impairments on all four tests, in particular, slower times on all time-limited tests. These results suggest the need for more time when completing neuropsychological tasks involving selected and focused attention, as well as cognitive flexibility, as a possible indicator of genetic vulnerability to schizophrenia.","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"16721500","pmcid":"PMC1705537","openalex_id":"https://openalex.org/W2017999835","authors":[],"funders":[],"total_grants":0,"fwci":2.0887,"citation_percentile":0.8513565,"influential_citations":0,"citation_trend":[{"year":2012,"count":6},{"year":2013,"count":1},{"year":2014,"count":1},{"year":2018,"count":1},{"year":2019,"count":1},{"year":2021,"count":1},{"year":2022,"count":1}],"oa_status":"hybrid","license":"cc-by-nc","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/s00787-006-0547-2.pdf","host_type":"journal"},{"url":"https://link.springer.com/content/pdf/10.1007/s00787-006-0547-2.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s00787-006-0547-2/fulltext.html","host_type":"publisher"},{"url":"http://link.springer.com/content/pdf/10.1007/s00787-006-0547-2.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1007/s00787-006-0547-2","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/16721500","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1705537","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC1705537","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC1705537?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Schizophrenia research and treatment","Attention Deficit Hyperactivity Disorder","Bipolar Disorder and Treatment","Adolescent","Attention","Cognition Disorders","Female","Frontal Lobe","Humans","Male","Neuropsychological Tests","Problem Solving","Psychometrics","Reaction Time","Schizophrenia","Schizotypal Personality Disorder","Siblings","Statistics as Topic"],"mesh_terms":["Adolescent","Attention","Cognition Disorders","Female","Frontal Lobe","Humans","Male","Neuropsychological Tests","Problem Solving","Psychometrics","Reaction Time","Schizophrenia","Schizotypal Personality Disorder","Statistics as Topic","Siblings"],"keywords":["Wisconsin Card Sorting Test","Cognitive flexibility","Executive functions","Psychology","Schizophrenia (object-oriented programming)","Neuropsychology","Trail Making Test","First-degree relatives","Neuropsychological test","Frontal lobe","Audiology","Cognition","Test (biology)","Developmental psychology","Clinical psychology","Psychiatry","Medicine","Family history"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T16:50:21.540097Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}