{"doi":"10.1007/s00335-021-09921-0","title":"Mouse Genome Informatics (MGI): latest news from MGD and GXD","abstract":"<jats:title>Abstract</jats:title><jats:p>The Mouse Genome Informatics (MGI) database system combines multiple expertly curated community data resources into a shared knowledge management ecosystem united by common metadata annotation standards. MGI’s mission is to facilitate the use of the mouse as an experimental model for understanding the genetic and genomic basis of human health and disease. MGI is the authoritative source for mouse gene, allele, and strain nomenclature and is the primary source of mouse phenotype annotations, functional annotations, developmental gene expression information, and annotations of mouse models with human diseases. MGI maintains mouse anatomy and phenotype ontologies and contributes to the development of the Gene Ontology and Disease Ontology and uses these ontologies as standard terminologies for annotation. The Mouse Genome Database (MGD) and the Gene Expression Database (GXD) are MGI’s two major knowledgebases. Here, we highlight some of the recent changes and enhancements to MGD and GXD that have been implemented in response to changing needs of the biomedical research community and to improve the efficiency of expert curation. MGI can be accessed freely at<jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"http://www.informatics.jax.org\">http://www.informatics.jax.org</jats:ext-link>.</jats:p>","journal":"Mammalian Genome","year":2022,"id":608745,"datarank":0.62147020895873,"base_score":4.143134726391533,"endowment":4.143134726391533,"self_citation_contribution":0.62147020895873,"citation_network_contribution":0.0,"self_endowment_contribution":0.62147020895873,"citer_contribution":0.0,"corpus_percentile":68.2,"corpus_rank":4190,"citation_count":62,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":29767,"name":"Joel E. Richardson","orcid":"0000-0003-3342-5753","position":1,"is_corresponding":false},{"id":227445,"name":"Richard M. Baldarelli","orcid":"0000-0002-5819-0228","position":2,"is_corresponding":false},{"id":11683,"name":"Judith A. Blake","orcid":"0000-0001-8522-334X","position":3,"is_corresponding":false},{"id":90567,"name":"James A. Kadin","orcid":"0000-0002-7644-3743","position":4,"is_corresponding":false},{"id":227446,"name":"Cynthia L. Smith","orcid":"0000-0003-3691-0324","position":5,"is_corresponding":false},{"id":11684,"name":"Carol J. Bult","orcid":"0000-0001-9433-210X","position":6,"is_corresponding":false},{"id":254862,"name":"Martin Ringwald","orcid":"0000-0002-5696-5421","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Mouse Genome Informatics (MGI): latest news from MGD and GXD.","abstract":"The Mouse Genome Informatics (MGI) database system combines multiple expertly curated community data resources into a shared knowledge management ecosystem united by common metadata annotation standards. MGI's mission is to facilitate the use of the mouse as an experimental model for understanding the genetic and genomic basis of human health and disease. MGI is the authoritative source for mouse gene, allele, and strain nomenclature and is the primary source of mouse phenotype annotations, functional annotations, developmental gene expression information, and annotations of mouse models with human diseases. MGI maintains mouse anatomy and phenotype ontologies and contributes to the development of the Gene Ontology and Disease Ontology and uses these ontologies as standard terminologies for annotation. The Mouse Genome Database (MGD) and the Gene Expression Database (GXD) are MGI's two major knowledgebases. Here, we highlight some of the recent changes and enhancements to MGD and GXD that have been implemented in response to changing needs of the biomedical research community and to improve the efficiency of expert curation. MGI can be accessed freely at http://www.informatics.jax.org .","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34698891","pmcid":"PMC8913530","openalex_id":null,"authors":[],"funders":[{"funder_name":"NHGRI NIH HHS","grant_id":"U24 HG010859","title":null},{"funder_name":"national institute of child health and human development","grant_id":"HD062499","title":null},{"funder_name":"NHGRI NIH HHS","grant_id":"P41 HG000330","title":null},{"funder_name":"NHGRI NIH HHS","grant_id":"U24 HG000330","title":null},{"funder_name":"national human genome research institute","grant_id":"HG000330","title":null},{"funder_name":"national human genome research institute","grant_id":"HG10859","title":null},{"funder_name":"NICHD NIH HHS","grant_id":"P41 HD062499","title":null},{"funder_name":"NHGRI NIH HHS","grant_id":"U41 HG000330","title":null},{"funder_name":"National Institutes of Health","grant_id":"5U24HG010859-05","title":"Alliance Central: A platform for sustainable development of next generation genome knowledgebases"},{"funder_name":"National Institutes of Health","grant_id":"5P41HD062499-07","title":"Gene Expression Database for Mouse Development"},{"funder_name":"National Institutes of Health","grant_id":"5U24HG000330-34","title":"Mouse Genome Database (MGD): A Core Knowledge Resource for Functional Characterization of the Human Genome"}],"total_grants":11,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"hybrid","license":"CC BY","oa_locations":[{"url":"https://europepmc.org/articles/PMC8913530","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC8913530?pdf=render","host_type":"Europe_PMC"},{"url":"https://doi.org/10.1007/s00335-021-09921-0","host_type":""},{"url":"https://link.springer.com/content/pdf/10.1007/s00335-021-09921-0.pdf","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/34698891","host_type":""},{"url":"http://dx.doi.org/10.1007/s00335-021-09921-0","host_type":""},{"url":"https://dx.doi.org/10.1007/s00335-021-09921-0","host_type":""},{"url":"https://doi.org/https://doi.org/10.1007/s00335-021-09921-0","host_type":""}],"fields_of_study":["0301 basic medicine","0303 health sciences","03 medical and health sciences"],"mesh_terms":["Animals","Mice","Genomics","Ecosystem","Alleles","Databases, Genetic","Gene Ontology"],"keywords":["Life Sciences","610","Genomics","Article","576","Databases","Mice","Gene Ontology","Genetic","Databases, Genetic","Medicine and Health Sciences","Animals","Alleles","Ecosystem","JMG"],"sdg_mappings":[{"sdg_number":3,"sdg_label":"3. Good health"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"gca"},{"name":"arrayexpress"},{"name":"refseq"},{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T21:19:44.693848Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}