{"doi":"10.1007/s00284-016-1078-9","title":"Effect of the Associated Methanogen Methanobrevibacter thaueri on the Dynamic Profile of End and Intermediate Metabolites of Anaerobic Fungus Piromyces sp. F1","abstract":null,"journal":"Current Microbiology","year":2016,"id":603958,"datarank":0.5533319181170905,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"self_citation_contribution":0.5533319181170905,"citation_network_contribution":0.0,"self_endowment_contribution":0.5533319181170905,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":39,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":546973,"name":"Wei Jin","orcid":"0000-0001-8263-571X","position":1,"is_corresponding":false},{"id":1381688,"name":"Yanfen Cheng","orcid":"0000-0001-8935-9551","position":2,"is_corresponding":false},{"id":567032,"name":"Weiyun Zhu","orcid":"0000-0001-9222-6581","position":3,"is_corresponding":false},{"id":1534109,"name":"Yuanfei Li","orcid":"0000-0002-0258-8843","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effect of the Associated Methanogen Methanobrevibacter thaueri on the Dynamic Profile of End and Intermediate Metabolites of Anaerobic Fungus Piromyces sp. F1","abstract":"Although the scheme of metabolic pathways involved in the production of the major end products has been described, the dynamic profile of metabolites of anaerobic fungi co-cultured with methanogens is limited, especially for the intermediate metabolites. In the present study, the fermentation of the co-culture of Piromyces sp. F1 and Methanobrevibacter thaueri on glucose was investigated. The presence of methanogens shortened the growth lag time of anaerobic fungi and enhanced the total gas production. The occurrence of the maximum cell dry weight and the disappearance of most of the substrate were observed at 24 h for the co-culture and 48 h for the fungal mono-culture. In the co-culture, hydrogen was detected at a very low level during fermentation, and formate transitorily accumulated at 24 h and disappeared at 48 h, resulting in an increase of pH. Acetate was higher during the fermentation in the co-culture (P < 0.05), while lactate and ethanol were higher only in the initial stage of fermentation (P < 0.05). After 48 h, lactate in the mono-culture became much higher than that in the co-culture (P < 0.05), and ethanol tended to remain the same in both cultures. Moreover, malate tended to be exhausted in the co-culture, while it accumulated in the mono-culture. Citrate was also detected in both co-culture and mono-culture. Collectively, these results suggest that methanogen enhanced the malate pathway and weakened the lactate pathway of anaerobic fungus.","is_dataset_classified":null,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"27287262","pmcid":null,"openalex_id":"https://openalex.org/W2410008680","authors":[],"funders":[{"funder_name":"the National Natural Science Foundation of China","grant_id":"31101735","title":null},{"funder_name":"the National Natural Science Foundation of China","grant_id":"31301999","title":null},{"funder_name":"the Fundamental Research Funds for the Central Universities","grant_id":"KYZ201312","title":null},{"funder_name":"the Fundamental Research Funds for the Central Universities","grant_id":"KYZ201412","title":null},{"funder_name":"Natural Science Foundation of Jiangsu Province","grant_id":"BK20141372","title":null}],"total_grants":5,"fwci":1.3899,"citation_percentile":0.81261991,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2018,"count":1},{"year":2019,"count":3},{"year":2020,"count":5},{"year":2021,"count":6},{"year":2022,"count":13},{"year":2023,"count":2},{"year":2024,"count":3},{"year":2025,"count":4},{"year":2026,"count":1}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/s00284-016-1078-9.pdf","host_type":"publisher"},{"url":"http://link.springer.com/article/10.1007/s00284-016-1078-9/fulltext.html","host_type":"publisher"},{"url":"http://link.springer.com/content/pdf/10.1007/s00284-016-1078-9","host_type":"publisher"},{"url":"https://doi.org/10.1007/s00284-016-1078-9","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/27287262","host_type":"repository"}],"fields_of_study":["Microbial Community Ecology and Physiology","Gut microbiota and health","Probiotics and Fermented Foods","Anaerobiosis","Coculture Techniques","Fermentation","Glucose","Hydrogen","Lactic Acid","Malates","Methane","Methanobrevibacter","Piromyces"],"mesh_terms":["Anaerobiosis","Fermentation","Glucose","Hydrogen","Malates","Methane","Coculture Techniques","Lactic Acid","Piromyces","Methanobrevibacter"],"keywords":["Methanogen","Fermentation","Biology","Anaerobic exercise","Mixed acid fermentation","Formate","Biochemistry","Ethanol","Microbiology","Metabolism","Bacteria","Lactic acid","Lactic acid fermentation"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T23:06:14.631276Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}