{"doi":"10.1007/s00277-024-05944-0","title":"Allogeneic hematopoietic cell transplantation from alternative donors in acute myeloid leukemia","abstract":null,"journal":"Annals of Hematology","year":2024,"id":608989,"datarank":0.33116486259002725,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.03927834023173023,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.03927834023173023,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":4,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1564786,"name":"Kaoru Morita","orcid":null,"position":1,"is_corresponding":false},{"id":1564787,"name":"Takaaki Konuma","orcid":null,"position":2,"is_corresponding":false},{"id":1564788,"name":"Masamitsu Yanada","orcid":null,"position":3,"is_corresponding":false},{"id":1564785,"name":"Junichi Sugita","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Allogeneic hematopoietic cell transplantation from alternative donors in acute myeloid leukemia","abstract":"Allogeneic hematopoietic cell transplantation (HCT) potentially provides a cure for patients with acute myeloid leukemia (AML) who are unlikely to be cured with chemotherapy alone. Previously, human leukocyte antigen (HLA)-matched related donors were used exclusively, which made the procedure available for a limited proportion of patients. The introduction of high-resolution HLA-typing technology, innovations in immunosuppressive therapy, and improved supportive care measures have significantly changed the situation. Now, patients without a matched related donor have an ample opportunity to receive allogeneic HCT with the use of matched or mismatched unrelated donors, umbilical cord blood grafts, or haploidentical related donors. The outcomes of alternative donor transplantations have improved over the past decades, and the growth of unrelated donor registries as well as the donor diversification have enhanced the chance of finding a suitable donor. With multiple alternative donor choices available for most patients, the donor selection is becoming increasingly important. To discuss the optimal donor choice in case of unavailability of an HLA-matched related donor, this article reviews the existing literature of retrospective and prospective comparisons of different alternative donor transplantations in AML and discusses the current state-of-art modalities in allogeneic HCT using alternative donors.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39153145","pmcid":null,"openalex_id":"https://openalex.org/W4401664754","authors":[],"funders":[{"funder_name":"Japan Society for the Promotion of Science","grant_id":"JP24K11566","title":null}],"total_grants":1,"fwci":1.819,"citation_percentile":0.85752029,"influential_citations":0,"citation_trend":[{"year":2025,"count":2},{"year":2026,"count":4}],"oa_status":"closed","license":"https://www.springernature.com/gp/researchers/text-and-data-mining","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/s00277-024-05944-0.pdf","host_type":"publisher"},{"url":"https://link.springer.com/article/10.1007/s00277-024-05944-0/fulltext.html","host_type":"publisher"},{"url":"https://doi.org/10.1007/s00277-024-05944-0","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39153145","host_type":"repository"}],"fields_of_study":["Hematopoietic Stem Cell Transplantation","Immune Cell Function and Interaction","T-cell and B-cell Immunology","Humans","Leukemia, Myeloid, Acute","Unrelated Donors","Transplantation, Homologous","Allografts","Histocompatibility Testing","Tissue Donors","Donor Selection","Cord Blood Stem Cell Transplantation"],"mesh_terms":["Histocompatibility Testing","Humans","Tissue Donors","Transplantation, Homologous","Leukemia, Myeloid, Acute","Hematopoietic Stem Cell Transplantation","Cord Blood Stem Cell Transplantation","Donor Selection","Unrelated Donors","Allografts"],"keywords":["Medicine","Transplantation","Human leukocyte antigen","Hematopoietic cell","Hematopoietic stem cell transplantation","Hematology","Oncology","Myeloid leukemia","Umbilical cord","Cord blood","Leukemia","Histocompatibility","Immunology","Internal medicine","Haematopoiesis","Stem cell","Antigen","Acute myeloid leukemia","Umbilical cord blood","Allogeneic Hematopoietic Cell Transplantation","Unrelated Donor","Haploidentical Related Donor"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-31T01:45:36.831681Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}