{"doi":"10.1007/s00270-024-03691-3","title":"Mechanical Venous Thrombectomy for Deep Venous Thrombosis in Cancer Patients: A Single-Center Retrospective Study","abstract":"PURPOSE: Venous thromboembolism (VTE) is a major contributor to the mortality of cancer patients. Mechanical thrombectomy (MT) is an endovascular technique that physically removes a thrombus without thrombolytics. The purpose of this study was to evaluate safety, efficacy, and clinical outcomes following MT for lower extremity DVT in cancer patients. METHODS: This single-center, retrospective study evaluated outcomes following MT of lower extremity DVT in cancer patients from November 2019 to May 2023. The primary outcome measure was clinical success, defined as a decrease in Villalta score by at least 2 points following the intervention. Secondary outcomes included repeat intervention-free survival and overall survival. Technical success was defined as restoring venous flow with mild (< 10%) or no residual filling defect. RESULTS: In total, 90 patients and 113 procedures were included. Technical and clinical success was achieved in 81% and 87% of procedures performed. Repeat intervention-free survival at 1 month, 3 months, and 6 months post-procedure was 92%, 82%, and 77%, respectively. The complication rate was 2.7%. Pathologic analysis of the extracted thrombus revealed tumor thrombus in 18.4% (18/98) samples. Overall survival for the study cohort was 87% at 1 month, 74% at 3 months, and 62% at 6 months. Patients who were found to have tumor thrombi were noted to have a decreased overall survival compared to patients with non-tumor thrombi (P = 0.012). CONCLUSION: MT is safe and efficacious in reducing cancer patients' VTE-related symptoms. The high rate of tumor thrombus in thrombectomy specimens suggests this phenomenon is more common than suspected.","journal":"CardioVascular and Interventional Radiology","year":2024,"id":435027,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":12,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9502,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1242180,"name":"Koustav Pal","orcid":"0000-0002-0777-2260","position":1,"is_corresponding":false},{"id":1242181,"name":"Syed Hadi Ahmed","orcid":"0000-0003-0144-0465","position":2,"is_corresponding":false},{"id":1242731,"name":"J. Kuban","orcid":null,"position":3,"is_corresponding":false},{"id":1047629,"name":"Milan Patel","orcid":"0000-0002-6805-5628","position":4,"is_corresponding":false},{"id":1241568,"name":"Ketan Y. Shah","orcid":"0000-0002-9764-5926","position":5,"is_corresponding":false},{"id":259896,"name":"Peiman Habibollahi","orcid":"0000-0003-2984-6782","position":6,"is_corresponding":false},{"id":1242182,"name":"Zeyad Metwalli","orcid":"0000-0003-0067-5115","position":7,"is_corresponding":false},{"id":1242183,"name":"Varshana Gurusamy","orcid":"0009-0007-9974-2790","position":8,"is_corresponding":false},{"id":452513,"name":"Sanjay Gupta","orcid":"0000-0001-7001-0130","position":9,"is_corresponding":false},{"id":942897,"name":"Cristhiam M. Rojas‐Hernandez","orcid":"0000-0003-3890-3929","position":10,"is_corresponding":false},{"id":548493,"name":"Vahid Afshar‐Kharghan","orcid":"0000-0003-2911-1284","position":11,"is_corresponding":false},{"id":1031038,"name":"Michael H. Kroll","orcid":"0000-0001-6817-5761","position":12,"is_corresponding":false},{"id":407607,"name":"Rahul A. Sheth","orcid":"0000-0001-9615-8985","position":13,"is_corresponding":false},{"id":1242730,"name":"Riya M. Patel","orcid":null,"position":0,"is_corresponding":true}],"reference_count":19,"raw_metadata":null,"created_at":"2026-07-19T02:00:03.406367Z","pmid":"38548981","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}