{"doi":"10.1007/bf03041329","title":"Bronchial hyperresponsiveness in Sjögren’s syndrome — relationship between extraglandular manifestation","abstract":null,"journal":"Japanese Journal of Rheumatology","year":1997,"id":671074,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1753061,"name":"Michifumi Kohno","orcid":null,"position":1,"is_corresponding":false},{"id":1753062,"name":"Masahiro Ieko","orcid":null,"position":2,"is_corresponding":false},{"id":1753063,"name":"Ryuji Matsuyama","orcid":null,"position":3,"is_corresponding":false},{"id":1361065,"name":"Akihiro Ohmoto","orcid":"0000-0002-3642-2032","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Bronchial hyperresponsiveness in Sjögren’s syndrome — relationship between extraglandular manifestation","abstract":"Our objective was to appraise bronchial hyperresponsiveness in Sjögren’s syndrome (SS) and to analyze the clinical aspects of those patients. Forty-five patients with primary and secondary SS underwent examination with chest X-ray, spirometry and directly writing of the dose-response curve of respiratory resistance (R rs ) during the continuous inhalation of methacholine in stepwise incremental concentrations (astograph). Thirty-one patients (68.9%) had bronchial hyperresponsiveness. Ten out of 12 (83.3%) patients with extraglandular involvement had bronchial hyperresponsiveness. The threshold of the increase of R rs in SS patients was significantly higher than bronchial asthma. This paper shows that some patients with SS have bronchial hyperresponsiveness; especially in patients with extraglandular involvement, it occurs at a high incidence. In addition, the pattern of the dose-response curve with bronchial hyperresponsiveness in SS was similar to that of chronic bronchitis rather than bronchial asthma in the methacholine inhalation test.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19162232","pmcid":null,"openalex_id":"https://openalex.org/W2125023482","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.14518292,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/BF03041329.pdf","host_type":"publisher"},{"url":"http://link.springer.com/article/10.1007/BF03041329/fulltext.html","host_type":"publisher"},{"url":"http://link.springer.com/content/pdf/10.1007/BF03041329","host_type":"publisher"},{"url":"https://doi.org/10.1007/bf03041329","host_type":"journal"}],"fields_of_study":["Salivary Gland Disorders and Functions","Asthma and respiratory diseases","Chronic Obstructive Pulmonary Disease (COPD) Research"],"mesh_terms":[],"keywords":["Bronchial hyperresponsiveness","Medicine","Methacholine","Asthma","Spirometry","Inhalation","Bronchitis","Chronic bronchitis","Internal medicine","Airway hyperresponsiveness","Bronchial hyperreactivity","Respiratory system","Gastroenterology","Immunology","Respiratory disease","Lung","Anesthesia"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-16T01:14:03.643939Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}