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Elucidation of HIV-induced cell surface effects may provide the basis for a rational approach to the design of antiviral agents which are selective for HIV-infected cells.</jats:p>","journal":"Bioscience Reports","year":1988,"id":615118,"datarank":0.4887144807032224,"base_score":3.258096538021482,"endowment":3.258096538021482,"self_citation_contribution":0.4887144807032224,"citation_network_contribution":0.0,"self_endowment_contribution":0.4887144807032224,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":25,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1585304,"name":"A. 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Both killing processes appear to involve cell surface effects of HIV. A model is proposed for the HIV-mediated cell surface processes which could result in cell-cell fusion and single cell killing. The purpose of this model is to define the potential roles of individual viral envelope and cell surface molecules in cell killing processes and to identify alternative routes to the establishment of persistently-infected cells. Elucidation of HIV-induced cell surface effects may provide the basis for a rational approach to the design of antiviral agents which are selective for HIV-infected cells.</jats:p>","is_dataset_classified":null,"base_score":3.258096538021482,"endowment":3.258096538021482,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"3293665","pmcid":"PMC7088091","openalex_id":"https://openalex.org/W1996216405","authors":[],"funders":[{"funder_name":"NIAID NIH HHS","grant_id":"AI-22720","title":null}],"total_grants":1,"fwci":0.7219,"citation_percentile":0.72352941,"influential_citations":0,"citation_trend":[{"year":2024,"count":1},{"year":2026,"count":1}],"oa_status":"hybrid","license":null,"oa_locations":[{"url":"https://portlandpress.com/bioscirep/article-pdf/8/1/35/472151/bsr0080035.pdf","host_type":"journal"},{"url":"https://portlandpress.com/bioscirep/article-pdf/8/1/35/472151/bsr0080035.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1007/bf01128970","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/3293665","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7088091","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC7088091","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC7088091?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["HIV Research and Treatment","HIV/AIDS drug development and treatment","Immune Cell Function and Interaction"],"mesh_terms":["Biological Transport, Active","Cell Fusion","Cell Membrane","Cells, Cultured","Cytopathogenic Effect, Viral","HIV","Humans","Models, Biological","Potassium","Receptors, Virus","Sodium","Viral Envelope Proteins","Receptors, HIV"],"keywords":["Cell fusion","Cell","Virology","Biology","Viral envelope","Virus","Cell biology","Human immunodeficiency virus (HIV)","Cell membrane","Genetics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T19:01:44.510527Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}