{"doi":"10.1007/bf00441431","title":"Constitutive expression of a cowpea trypsin inhibitor gene, CpTi, in transgenic rice plants confers resistance to two major rice insect pests","abstract":null,"journal":"Molecular Breeding","year":1996,"id":598411,"datarank":0.7954957362088615,"base_score":5.303304908059076,"endowment":5.303304908059076,"self_citation_contribution":0.7954957362088615,"citation_network_contribution":0.0,"self_endowment_contribution":0.7954957362088615,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":200,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1533358,"name":"Qingzhong Xue","orcid":null,"position":1,"is_corresponding":false},{"id":1533360,"name":"David McElroy","orcid":null,"position":2,"is_corresponding":false},{"id":1533362,"name":"Yogesh Mawal","orcid":null,"position":3,"is_corresponding":false},{"id":1533363,"name":"Vaughan A. Hilder","orcid":null,"position":4,"is_corresponding":false},{"id":1533365,"name":"Ray Wu","orcid":null,"position":5,"is_corresponding":false},{"id":1533356,"name":"Deping Xu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Constitutive expression of a cowpea trypsin inhibitor gene, CpTi, in transgenic rice plants confers resistance to two major rice insect pests","abstract":"The gene encoding a cowpea trypsin inhibitor (CpTI), which confers insect resistance in transgenic tobacco, was introduced into rice. Expression of the CpTi gene driven by the constitutively active promoter of the rice actin 1 gene (Act1) leads to high-level accumulation of the CpTI protein in transgenic rice plants. Protein extracts from transgenic rice plants exhibit a strong inhibitory activity against bovine trypsin, suggesting that the proteinase inhibitor produced in transgenic rice is functionally active. Small-scale field tests showed that the transgenic rice plants expressing the CpTi gene had significantly increased resistance to two species of rice stem borers, which are major rice insect pests. Our results suggest that the cowpea trypsin inhibitor may be useful for the control of rice insect pests.","is_dataset_classified":null,"base_score":5.303304908059076,"endowment":5.303304908059076,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W1972587812","authors":[],"funders":[],"total_grants":0,"fwci":4.7784,"citation_percentile":0.95908913,"influential_citations":0,"citation_trend":[{"year":2012,"count":15},{"year":2013,"count":5},{"year":2014,"count":2},{"year":2015,"count":1},{"year":2016,"count":6},{"year":2017,"count":6},{"year":2018,"count":3},{"year":2019,"count":1},{"year":2020,"count":4},{"year":2021,"count":8},{"year":2022,"count":6},{"year":2023,"count":2},{"year":2024,"count":2},{"year":2025,"count":1},{"year":2026,"count":2}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/BF00441431.pdf","host_type":"publisher"},{"url":"http://link.springer.com/article/10.1007/BF00441431/fulltext.html","host_type":"publisher"},{"url":"http://link.springer.com/content/pdf/10.1007/BF00441431","host_type":"publisher"},{"url":"https://doi.org/10.1007/bf00441431","host_type":"journal"}],"fields_of_study":["Insect Resistance and Genetics","Agricultural pest management studies","Transgenic Plants and Applications"],"mesh_terms":[],"keywords":["Biology","Genetically modified crops","Genetically modified rice","Trypsin inhibitor","Transgene","Gene","Insect","Trypsin","Oryza sativa","Gene expression","Botany","Biochemistry","Enzyme"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T15:39:49.408536Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}