{"doi":"10.1007/978-3-030-03502-0_7","title":"HPV-Associated Anal Cancer in the HIV/AIDS Patient","abstract":null,"journal":"Cancer Treatment and Research","year":2019,"id":607687,"datarank":0.62147020895873,"base_score":4.143134726391533,"endowment":4.143134726391533,"self_citation_contribution":0.62147020895873,"citation_network_contribution":0.0,"self_endowment_contribution":0.62147020895873,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":62,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":265771,"name":"Joel M. Palefsky","orcid":"0000-0002-5097-3818","position":1,"is_corresponding":false},{"id":1070214,"name":"Chia-Ching J. Wang","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"HPV-Associated Anal Cancer in the HIV/AIDS Patient","abstract":"The prevalence of anal human papillomavirus (HPV) infection and anal high-grade squamous intraepithelial lesion (HSIL) remain high among HIV-infected individuals on effective antiretroviral therapy (ART). The incidence of HPV-related anal cancers has continued to increase since the introduction of ART. Therefore, ART may confer only limited benefit with respect to reducing the risk of anal HSIL and cancer. Efforts are in progress to define the efficacy of secondary prevention programs for prevention of anal cancer. In the modern ART era, anal cancer recurrence and survival outcomes are similar in HIV-infected and HIV-uninfected patients, but HIV-infected patients may experience more toxicities. This article reviews the current literature on HPV-associated anal cancer in the HIV-infected population, including epidemiology, screening, clinical characteristics, and treatment outcomes.","is_dataset_classified":null,"base_score":4.143134726391533,"endowment":4.143134726391533,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30523625","pmcid":null,"openalex_id":"https://openalex.org/W2905379667","authors":[],"funders":[],"total_grants":0,"fwci":41.7759,"citation_percentile":0.99807956,"influential_citations":0,"citation_trend":[{"year":2019,"count":2},{"year":2020,"count":5},{"year":2021,"count":11},{"year":2022,"count":11},{"year":2023,"count":12},{"year":2024,"count":9},{"year":2025,"count":6},{"year":2026,"count":4}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/978-3-030-03502-0_7","host_type":"publisher"},{"url":"https://doi.org/10.1007/978-3-030-03502-0_7","host_type":"book series"},{"url":"https://pubmed.ncbi.nlm.nih.gov/30523625","host_type":"repository"}],"fields_of_study":["Colorectal and Anal Carcinomas","Cervical Cancer and HPV Research","Viral-associated cancers and disorders","Acquired Immunodeficiency Syndrome","Anti-Retroviral Agents","Anus Neoplasms","Coinfection","Early Detection of Cancer","HIV Infections","Humans","Papillomaviridae","Papillomavirus Infections"],"mesh_terms":["Acquired Immunodeficiency Syndrome","Anus Neoplasms","Humans","HIV Infections","Papillomaviridae","Papillomavirus Infections","Anti-Retroviral Agents","Early Detection of Cancer","Coinfection"],"keywords":["Anal cancer","Medicine","HPV vaccines","Human immunodeficiency virus (HIV)","Antiretroviral therapy","Population","Incidence (geometry)","Epidemiology","Cervical cancer","Human papillomavirus","Cancer","Squamous intraepithelial lesion","Oncology","HPV infection","Gynecology","Internal medicine","Immunology","Viral load","Cervical intraepithelial neoplasia","Environmental health","HIV","Vaccination","immunosuppression","HPV"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T06:49:49.179325Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}