{"doi":"10.1007/978-1-4939-7095-7_10","title":"Isolation and Characterization of Mouse and Human Follicular Dendritic Cells","abstract":null,"journal":"Methods in Molecular Biology","year":2017,"id":639711,"datarank":0.4330048323409193,"base_score":2.639057329615259,"endowment":2.639057329615259,"self_citation_contribution":0.3958585994422889,"citation_network_contribution":0.03714623289863041,"self_endowment_contribution":0.3958585994422889,"citer_contribution":0.03714623289863041,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":5,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":355105,"name":"Riham El Sayed","orcid":"0000-0002-8634-5872","position":1,"is_corresponding":false},{"id":226247,"name":"Costantino Pitzalis","orcid":"0000-0003-1326-5051","position":2,"is_corresponding":false},{"id":1662256,"name":"Mohey Eldin M. El Shikh","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Isolation and Characterization of Mouse and Human Follicular Dendritic Cells","abstract":"Follicular dendritic cells (FDCs) reside in the B cell follicles of secondary and tertiary lymphoid tissues where they play key roles in the development and maintenance of lymphoid tissue architecture and function. FDCs trap native antigens for extended periods of time in the form of immune complexes which critcally regulate germinal center reactions in health and disease. Here, we describe how to isolate and characterize FDCs from murine and human lymphoid tissues.","is_dataset_classified":null,"base_score":2.639057329615259,"endowment":2.639057329615259,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28589352","pmcid":null,"openalex_id":"https://openalex.org/W2623962952","authors":[],"funders":[],"total_grants":0,"fwci":5.5786,"citation_percentile":0.95643818,"influential_citations":0,"citation_trend":[{"year":2019,"count":1},{"year":2020,"count":9},{"year":2022,"count":2},{"year":2025,"count":1}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/978-1-4939-7095-7_10","host_type":"publisher"},{"url":"https://doi.org/10.1007/978-1-4939-7095-7_10","host_type":"book series"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28589352","host_type":"repository"},{"url":"http://qmro.qmul.ac.uk/xmlui/handle/123456789/28692","host_type":"repository"}],"fields_of_study":["Immunotherapy and Immune Responses","Immune Cell Function and Interaction","T-cell and B-cell Immunology","Animals","Biomarkers","Cell Separation","Dendritic Cells, Follicular","Flow Cytometry","Fluorescent Antibody Technique","Germinal Center","Humans","Immunomagnetic Separation","Immunophenotyping","Lymph Nodes","Mice","Spleen"],"mesh_terms":["Animals","Cell Separation","Flow Cytometry","Fluorescent Antibody Technique","Humans","Lymph Nodes","Spleen","Biomarkers","Immunophenotyping","Immunomagnetic Separation","Germinal Center","Dendritic Cells, Follicular","Mice"],"keywords":["Follicular dendritic cells","Germinal center","Immune system","Follicular phase","Biology","Lymphatic system","Dendritic cell","Function (biology)","Immunology","Cell biology","B cell","Antigen-presenting cell","T cell","Antibody","Genetics","Spleen","Lymph nodes","Tonsil","Fdc Isolation","Germinal Center, Gcr"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T01:21:32.573202Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}