{"doi":"10.1007/978-1-4615-2904-0_51","title":"The Oxidation of Aldehydes by Horse Liver Alcohol Dehydrogenase","abstract":null,"journal":"Advances in Experimental Medicine and Biology","year":1993,"id":596391,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1527447,"name":"George L. Kenyon","orcid":null,"position":1,"is_corresponding":false},{"id":1527448,"name":"Norman J. Oppenheimer","orcid":null,"position":2,"is_corresponding":false},{"id":1527446,"name":"Gary T. M. Henehan","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Oxidation of Aldehydes by Horse Liver Alcohol Dehydrogenase","abstract":"A lag phase in the spectrophotometric assay progress curve of aldehyde oxidation by HL-ADH was observed and characterised. The aldehyde oxidation and aldehyde dismutation reactions were shown to be related, and a mechanism to explain net aldehyde oxidation was proposed. The spectrophotometric assay was shown to be unsuitable for measurement of kinetic parameters for aldehyde oxidation by HL-ADH, and kinetic constants previously determined were shown to be in error. Existing data on the aldehyde dismutation reaction are insufficient to discount a role for HL-ADH in aldehyde transformation in vivo.","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"8493927","pmcid":null,"openalex_id":"https://openalex.org/W114986331","authors":[],"funders":[{"funder_name":"NIGMS NIH HHS","grant_id":"GM-22982","title":null},{"funder_name":"NIAMS NIH HHS","grant_id":"AR-17323","title":null}],"total_grants":2,"fwci":0.0,"citation_percentile":0.10804598,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://www.springernature.com/gp/researchers/text-and-data-mining","oa_locations":[{"url":"https://link.springer.com/content/pdf/10.1007/978-1-4615-2904-0_51","host_type":"publisher"},{"url":"https://doi.org/10.1007/978-1-4615-2904-0_51","host_type":"book series"},{"url":"https://pubmed.ncbi.nlm.nih.gov/8493927","host_type":"repository"}],"fields_of_study":["Alcohol Consumption and Health Effects"],"mesh_terms":["Alcohol Dehydrogenase","Aldehydes","Animals","Horses","Kinetics","Liver","Models, Chemical","NAD","Magnetic Resonance Spectroscopy","Oxidation-Reduction","Spectrophotometry, Ultraviolet","Substrate Specificity","In Vitro Techniques"],"keywords":["Aldehyde","Aldehyde dehydrogenase","Chemistry","Alcohol oxidation","Alcohol dehydrogenase","Alcohol","Catalysis","Organic chemistry","Enzyme"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T10:07:10.069642Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}