{"doi":"10.1007/978-1-0716-2115-8_15","title":"AIRR Community Guide to Planning and Performing AIRR-Seq Experiments","abstract":"The development of high-throughput sequencing of adaptive immune receptor repertoires (AIRR-seq of IG and TR rearrangements) has provided a new frontier for in-depth analysis of the immune system. The last decade has witnessed an explosion in protocols, experimental methodologies, and computational tools. In this chapter, we discuss the major considerations in planning a successful AIRR-seq experiment together with basic strategies for controlling and evaluating the outcome of the experiment. Members of the AIRR Community have authored several chapters in this edition, which cover step-by-step instructions to successfully conduct, analyze, and share an AIRR-seq project.","journal":"Methods in molecular biology","year":2022,"id":276765,"datarank":0.36675861743646426,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.03717493083603131,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.03717493083603131,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":4,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9448,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":947324,"name":"Magnolia L. Bostick","orcid":"0000-0002-2449-4995","position":1,"is_corresponding":false},{"id":947325,"name":"Nidhi Gupta","orcid":"0000-0002-2347-9339","position":2,"is_corresponding":false},{"id":2819,"name":"Encarnita Mariotti‐Ferrandiz","orcid":"0000-0002-8770-0186","position":3,"is_corresponding":false},{"id":947752,"name":"Gloria Kraus","orcid":null,"position":4,"is_corresponding":false},{"id":108193,"name":"Wenzhao Meng","orcid":"0000-0002-8040-7825","position":5,"is_corresponding":false},{"id":320202,"name":"Cinque Soto","orcid":"0000-0002-3997-6217","position":6,"is_corresponding":false},{"id":414021,"name":"Johannes Trück","orcid":"0000-0002-0418-7381","position":7,"is_corresponding":false},{"id":942236,"name":"Ulrik Stervbo","orcid":"0000-0002-2831-8868","position":8,"is_corresponding":false},{"id":244597,"name":"Eline T. Luning Prak","orcid":"0000-0002-9478-9211","position":9,"is_corresponding":false},{"id":942705,"name":"on behalf of the AIRR Community","orcid":null,"position":10,"is_corresponding":false},{"id":685088,"name":"Anne Eugster","orcid":"0000-0001-8009-5959","position":0,"is_corresponding":true}],"reference_count":68,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T00:28:30.709588Z","pmid":"35622331","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}