{"doi":"10.1007/978-1-0716-0199-0_9","title":"Coalescent Simulation with msprime","abstract":"<jats:title>Abstract</jats:title><jats:p>Coalescent simulation is a fundamental tool in modern population genetics. The  library provides unprecedented scalability in terms of both the simulations that can be performed and the efficiency with which the results can be processed. We show how coalescent models for population structure and demography can be constructed using a simple Python API, as well as how we can process the results of such simulations to efficiently calculate statistics of interest. We illustrate ’s flexibility by implementing a simple (but functional) approximate Bayesian computation inference method in just a few tens of lines of code.</jats:p>","journal":"Methods in Molecular Biology","year":2020,"id":619315,"datarank":0.5456379239589579,"base_score":3.6375861597263857,"endowment":3.6375861597263857,"self_citation_contribution":0.5456379239589579,"citation_network_contribution":0.0,"self_endowment_contribution":0.5456379239589579,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":37,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":615892,"name":"Konrad Lohse","orcid":"0000-0001-9918-058X","position":1,"is_corresponding":false},{"id":16824,"name":"Jerome Kelleher","orcid":"0000-0002-7894-5253","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Coalescent Simulation with msprime","abstract":"<jats:title>Abstract</jats:title><jats:p>Coalescent simulation is a fundamental tool in modern population genetics. 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