{"doi":"10.1007/3-540-46593-6_9","title":"The Graphical User Interface","abstract":null,"journal":"Lecture Notes in Computer Science","year":1999,"id":595621,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1525244,"name":"Xiaoyuan Tu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Graphical User Interface","abstract":"BACKGROUND: Stereotactic ablative body radiation (SABR), combined with systemic therapy (ST), is increasingly used to improve survival in oligometastatic breast cancer (OMBC).\nMETHODS: Patients with no brain or bone metastases on whole-body PET-CT received curative-intent local and systemic treatment, including SABR to metastatic site. Doses were: liver (45-50 Gy/5 fractions), peripheral lung (54 Gy/3fractions), central lung (60 Gy/8fractions), lymph nodes (30 Gy/3fractions), and peritoneal deposits (45 Gy/5fractions). Response was assessed at 3 months (RECIST v1.1); pain, gross tumour volume (GTV), planning target volume (PTV), and toxicity (CTCAE) were documented.\nRESULTS: From Dec 2021 to Mar 2025, 39 patients (42 sites; median age 47) were treated: liver (17), lung (14), nodes (5), other (6). At a median follow-up of 23.9 months, median PFS was 16.3 months (95% CI: 10.3-24.1); median OS was not reached; restricted mean OS for the cohort was 89.2 months. Twenty-eight patients were alive, 11 died, two were lost to follow-up. Subtypes included TNBC (36%) and HER2+ (33%), luminal B (23%). Univariate analysis showed older age, smaller PTV, and higher BED10 improved PFS; multivariate analysis confirmed age (HR 0.20, p = 0.006), PTV (HR 6.57, p = 0.001), and luminal subtype. Most common toxicity: grade 2 pain flare and hepatitis (10%).\nCONCLUSION: Curative-intent treatment with SABR for visceral OMBC offers promising survival outcomes. Molecular subtyping may aid treatment selection.\nCLINICAL TRIAL NUMBER: Not applicable.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"42432052","pmcid":null,"openalex_id":"https://openalex.org/W2477652530","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2023,"count":4}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://link.springer.com/content/pdf/10.1007/3-540-46593-6_9","host_type":"publisher"},{"url":"https://doi.org/10.1007/3-540-46593-6_9","host_type":"book series"}],"fields_of_study":["Human Motion and Animation","Humans","Female","Radiosurgery","Breast Neoplasms","Middle Aged","Adult","Aged","Combined Modality Therapy","Treatment Outcome","Positron Emission Tomography Computed Tomography","Neoplasm Metastasis"],"mesh_terms":["Humans","Female","Radiosurgery","Breast Neoplasms","Middle Aged","Adult","Aged","Combined Modality Therapy","Treatment Outcome","Positron Emission Tomography Computed Tomography","Neoplasm Metastasis"],"keywords":["Computer science","Graphical user interface","User interface","Human–computer interaction","Animation","Graphical user interface testing","10-foot user interface","Interface (matter)","Natural user interface","Multiple document interface","Computer graphics (images)","Computer animation","User interface design","Programming language","Operating system","Breast cancer","Metastasis","Oligo-metastasis","Stereotactic ablative body radiation (SABR)","Visceral"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-27T17:42:29.518950Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}