{"doi":"10.1006/geno.2000.6270","title":"Development of a 1.4-Mb BAC/PAC Contig and Physical Map within the Critical Region for Complete X-Linked Congenital Stationary Night Blindness in Xp11.4","abstract":null,"journal":"Genomics","year":2000,"id":607842,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1553323,"name":"C.G. Summer","orcid":null,"position":1,"is_corresponding":false},{"id":1553321,"name":"K.M. Boycott","orcid":null,"position":2,"is_corresponding":false},{"id":1553322,"name":"R.J. Zahorchak","orcid":null,"position":3,"is_corresponding":false},{"id":1553329,"name":"N.T. Bech-Hansen","orcid":null,"position":4,"is_corresponding":false},{"id":1560879,"name":"R.L. Sparkes","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Development of a 1.4-Mb BAC/PAC Contig and Physical Map within the Critical Region for Complete X-Linked Congenital Stationary Night Blindness in Xp11.4","abstract":"A physical map internal to the markers DXS1368 and DXS228 was developed for the p11.4 region of the human X chromosome. Twenty-four BACs and 10 PACs with an average insert size of 149 kb were aligned to form a contig across an estimated 1.4 Mb of DNA. This contig, which has on average fourfold clone coverage, was assembled by STS and EST content analysis using 46 markers, including 8 ESTs, two retinally expressed genes, and 22 new STSs developed from BAC- and PAC-derived DNA sequence. The average intermarker distance was 30 kb. This physical map provides resources for high-resolution mapping as well as suitable clones for large-scale sequencing efforts in Xp11.4, a region known to contain the gene for complete X-linked congenital stationary night blindness.","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"10950933","pmcid":null,"openalex_id":"https://openalex.org/W2074936491","authors":[],"funders":[{"funder_name":"Fighting Blindness Canada","grant_id":"RG9505","title":null}],"total_grants":1,"fwci":0.1222,"citation_percentile":0.48622541,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0888754300962700?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0888754300962700?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1006/geno.2000.6270","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/10950933","host_type":"repository"}],"fields_of_study":["Retinal Development and Disorders","Photoreceptor and optogenetics research","Connexins and lens biology","Bacteriophages","Chromosomes, Bacterial","DNA","Genetic Linkage","Humans","Microsatellite Repeats","Night Blindness","Physical Chromosome Mapping","Sequence Tagged Sites","X Chromosome"],"mesh_terms":["Bacteriophages","Chromosomes, Bacterial","DNA","Humans","Genetic Linkage","Night Blindness","X Chromosome","Sequence Tagged Sites","Microsatellite Repeats","Physical Chromosome Mapping"],"keywords":["Contig","Biology","Sequence-tagged site","Genetics","Bacterial artificial chromosome","Gene mapping","Physical mapping","Insert (composites)","clone (Java method)","Restriction map","Gene","DNA sequencing","X chromosome","Chromosome","Nucleic acid sequence","Genome"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T07:06:24.823828Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}