{"doi":"10.1002/ppul.25661","title":"Chest X‐ray lung imaging features in pediatric COVID‐19 and comparison with viral lower respiratory infections in young children","abstract":"RATIONALE: Chest radiography (CXR) is a noninvasive imaging approach commonly used to evaluate lower respiratory tract infections (LRTIs) in children. However, the specific imaging patterns of pediatric coronavirus disease 2019 (COVID-19) on CXR, their relationship to clinical outcomes, and the possible differences from LRTIs caused by other viruses in children remain to be defined. METHODS: This is a cross-sectional study of patients seen at a pediatric hospital with polymerase chain reaction (PCR)-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 95). Patients were subdivided in infants (0-2 years, n = 27), children (3-10 years, n = 27), and adolescents (11-19 years, n = 41). A sample of young children (0-2 years, n = 68) with other viral lower respiratory infections (LRTI) was included to compare their CXR features with the subset of infants (0-2 years) with COVID-19. RESULTS: Forty-five percent of pediatric patients with COVID-19 were hospitalized and 20% required admission to intensive care unit (ICU). The most common abnormalities identified were ground-glass opacifications (GGO)/consolidations (35%) and increased peribronchial markings/cuffing (33%). GGO/consolidations were more common in older individuals and perihilar markings were more common in younger subjects. Subjects requiring hospitalization or ICU admission had significantly more GGO/consolidations in CXR (p < .05). Typical CXR features of pediatric viral LRTI (e.g., hyperinflation) were more common in non-COVID-19 viral LRTI cases than in COVID-19 cases (p < .05). CONCLUSIONS: CXR may be a complemental exam in the evaluation of moderate or severe pediatric COVID-19 cases. The severity of GGO/consolidations seen in CXR is predictive of clinically relevant outcomes. Hyperinflation could potentially aid clinical assessment in distinguishing COVID-19 from other types of viral LRTI in young children.","journal":"Pediatric Pulmonology","year":2021,"id":188597,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9674,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":291825,"name":"José Moltó","orcid":"0000-0003-4564-1963","position":1,"is_corresponding":false},{"id":716765,"name":"Hector Aguilar","orcid":"0000-0002-4519-1790","position":2,"is_corresponding":false},{"id":315297,"name":"Jonathan Zember","orcid":"0000-0002-6522-4713","position":3,"is_corresponding":false},{"id":315298,"name":"Ramon Sanchez","orcid":"0000-0003-0100-3230","position":4,"is_corresponding":false},{"id":750468,"name":"Carlos Tor Díez","orcid":null,"position":5,"is_corresponding":false},{"id":750469,"name":"Pooneh R. Tabrizi","orcid":null,"position":6,"is_corresponding":false},{"id":730519,"name":"Bilal Mohammed","orcid":null,"position":7,"is_corresponding":false},{"id":446726,"name":"Jered Weinstock","orcid":"0000-0002-1892-7475","position":8,"is_corresponding":false},{"id":447974,"name":"Xilei Xuchen","orcid":null,"position":9,"is_corresponding":false},{"id":728621,"name":"R. Kahanowitch","orcid":"0000-0003-2856-5460","position":10,"is_corresponding":false},{"id":447973,"name":"Maria Arroyo","orcid":null,"position":11,"is_corresponding":false},{"id":315300,"name":"Marius George Linguraru","orcid":"0000-0001-6175-8665","position":12,"is_corresponding":false},{"id":315296,"name":"Gustavo Niño","orcid":"0000-0001-8621-6109","position":0,"is_corresponding":true}],"reference_count":36,"raw_metadata":null,"created_at":"2026-07-18T23:49:10.350554Z","pmid":"34487422","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}