{"doi":"10.1002/pbc.26188","title":"The relationship between cognitive and neuroimaging outcomes in children treated for acute lymphoblastic leukemia with chemotherapy only: A systematic review","abstract":null,"journal":"Pediatric Blood & Cancer","year":2017,"id":624679,"datarank":0.5533319181170905,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"self_citation_contribution":0.5533319181170905,"citation_network_contribution":0.0,"self_endowment_contribution":0.5533319181170905,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":39,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1614913,"name":"Marc Seal","orcid":null,"position":1,"is_corresponding":false},{"id":1014111,"name":"Vicki Anderson","orcid":"0000-0001-5233-3147","position":2,"is_corresponding":false},{"id":1614914,"name":"Maria McCarthy","orcid":null,"position":3,"is_corresponding":false},{"id":1614915,"name":"Madeleine Connellan","orcid":null,"position":4,"is_corresponding":false},{"id":452801,"name":"Peter Downie","orcid":"0000-0002-2017-9007","position":5,"is_corresponding":false},{"id":1614916,"name":"Cinzia De Luca","orcid":null,"position":6,"is_corresponding":false},{"id":1614912,"name":"Simone Hearps","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The relationship between cognitive and neuroimaging outcomes in children treated for acute lymphoblastic leukemia with chemotherapy only: A systematic review","abstract":"Cognitive late-effects have been identified in patients treated with chemotherapy-only protocols for childhood acute lymphoblastic leukemia (ALL), yet the underlying neuropathology is not well understood. This review synthesized recent findings from eight articles investigating the relationship between neurocognitive and neuroimaging outcomes for patients treated for ALL with chemotherapy-only protocols. Reported cognitive domains, imaging methods, and neuroanatomy examined were variable. Despite this, 62.5% (n = 5) of the reviewed studies found a significant relationship between cognitive and imaging outcomes. Greater understanding of the effects of treatment on neuroanatomy and cognitive outcomes is critical for proactively managing ALL cognitive late-effects. Research directions are suggested.","is_dataset_classified":null,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"27696698","pmcid":null,"openalex_id":"https://openalex.org/W2529273376","authors":[],"funders":[{"funder_name":"The Royal Children's Hospital Foundation","grant_id":"","title":null},{"funder_name":"Victorian Government Infrastructure Funding","grant_id":"","title":null},{"funder_name":"Leukaemia Foundation","grant_id":"","title":null}],"total_grants":3,"fwci":1.0145,"citation_percentile":0.68675722,"influential_citations":0,"citation_trend":[{"year":2017,"count":4},{"year":2018,"count":4},{"year":2019,"count":5},{"year":2020,"count":5},{"year":2021,"count":9},{"year":2022,"count":2},{"year":2023,"count":4},{"year":2024,"count":1},{"year":2025,"count":3},{"year":2026,"count":2}],"oa_status":"bronze","license":"http://doi.wiley.com/10.1002/tdm_license_1","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pbc.26188","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pbc.26188","host_type":"publisher"},{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fpbc.26188","host_type":"publisher"},{"url":"http://onlinelibrary.wiley.com/wol1/doi/10.1002/pbc.26188/fullpdf","host_type":"publisher"},{"url":"https://doi.org/10.1002/pbc.26188","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/27696698","host_type":"repository"},{"url":"http://hdl.handle.net/11343/291810","host_type":"repository"}],"fields_of_study":["Cancer-related cognitive impairment studies","Childhood Cancer Survivors' Quality of Life","Glioma Diagnosis and Treatment"],"mesh_terms":["Antineoplastic Combined Chemotherapy Protocols","Child","Cognition Disorders","Humans","Neuropsychological Tests","Prognosis","Precursor Cell Lymphoblastic Leukemia-Lymphoma","Neuroimaging"],"keywords":["Neurocognitive","Neuroimaging","Medicine","Neuropathology","Cognition","Lymphoblastic Leukemia","Neuroanatomy","Chemotherapy","Pathology","Leukemia","Psychiatry","Internal medicine","Disease","Acute lymphoblastic leukemia","Pediatric"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-04T04:30:37.853264Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}