{"doi":"10.1002/open.202100154","title":"First Isolation and Structure Elucidation of GDNT‐β‐Glu – Tetraether Lipid Fragment from Archaeal <i>Sulfolobus</i> Strains","abstract":"<jats:title>Abstract</jats:title><jats:p>Due to their special chemical structure, tetraether lipids (TEL) represent essential elements of archaeal membranes, providing these organisms with extraordinary properties. Here we describe the characterization of a newly isolated structural element of the main lipids. The TEL fragment GDNT‐β‐Glu was isolated from <jats:italic>Sulfolobus metallicus</jats:italic> and characterized in terms of its chemical structure by NMR‐ and MS‐investigations. The obtained data are dissimilar to analogically derived established structures – in essence, the binding relationships in the polar head group are re‐determined and verified. With this work, we provide an important contribution to the structure elucidation of intact TEL also contained in other <jats:italic>Sulfolobus</jats:italic> strains such as <jats:italic>Solfulobus acidocaldarius</jats:italic> and <jats:italic>Sulfolobus solfataricus</jats:italic>.</jats:p>","journal":"ChemistryOpen","year":2021,"id":19333,"datarank":0.26020806901386756,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.05226391484588394,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.05226391484588394,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":2,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":131366,"name":"Christoph Hübner","orcid":null,"position":1,"is_corresponding":false},{"id":131368,"name":"Dieter Ströhl","orcid":null,"position":2,"is_corresponding":false},{"id":131369,"name":"Olaf Scheufler","orcid":null,"position":3,"is_corresponding":false},{"id":131370,"name":"Steffen Czich","orcid":null,"position":4,"is_corresponding":false},{"id":131371,"name":"Julia M. Börke","orcid":null,"position":5,"is_corresponding":false},{"id":131372,"name":"Gerhard Hildebrand","orcid":null,"position":6,"is_corresponding":false},{"id":131373,"name":"Klaus Liefeith","orcid":null,"position":7,"is_corresponding":false},{"id":131364,"name":"Alexander Scholte","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34468091","pmcid":"PMC8409090","openalex_id":"https://openalex.org/W3197299031","authors":[],"funders":[{"funder_name":"Bundesministerium für Bildung und Forschung (Germany)","grant_id":"03XP0044E","title":null},{"funder_name":"Bundesministerium für Bildung und Forschung (Germany)","grant_id":"13GW0082E","title":null}],"total_grants":2,"fwci":0.2272,"citation_percentile":0.55228967,"influential_citations":0,"citation_trend":[{"year":2021,"count":1},{"year":2023,"count":1},{"year":2025,"count":1}],"oa_status":"gold","license":"cc-by-sa","oa_locations":[{"url":"https://doi.org/10.1002/open.202100154","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/open.202100154","host_type":"GOLD"},{"url":"https://doi.org/10.1002/open.202100154","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/open.202100154","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/open.202100154","host_type":"publisher"},{"url":"https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/open.202100154","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34468091","host_type":"repository"},{"url":"https://doaj.org/article/0eec57d2ba944af6a3dfffce95fe28be","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8409090","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC8409090","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC8409090?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Methane Hydrates and Related Phenomena","Enzyme Structure and Function","Lipid Membrane Structure and Behavior","Medicine","Chemistry","Biology","Environmental Science","Carbon-13 Magnetic Resonance Spectroscopy","Cyclization","Diglycerides","Glycolipids","Mass Spectrometry","Membrane Lipids","Sulfolobus"],"mesh_terms":["Cyclization","Diglycerides","Glycolipids","Membrane Lipids","Mass Spectrometry","Sulfolobus","Carbon-13 Magnetic Resonance Spectroscopy"],"keywords":["Sulfolobus acidocaldarius","Sulfolobus solfataricus","Sulfolobus","Archaea","Chemistry","Stereochemistry","Lipid II","Biochemistry","Enzyme","Biosynthesis","Structure elucidation","Mass spectrometry","Nmr Spectroscopy","Tetraether Lipids"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-04T03:21:02.428612Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}