{"doi":"10.1002/oby.24285","title":"Functional mobility and pain are improved for 6 years after adolescent bariatric surgery","abstract":"OBJECTIVE: The long-term durability of improvements in functional mobility and musculoskeletal pain for adolescents after metabolic and bariatric surgery (MBS) is unknown. METHODS: We used the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study to determine the change in mobility and pain among adolescents who underwent MBS. From standardized 400-m walk tests, we analyzed walk time, heart rate (HR) parameters, and musculoskeletal pain. RESULTS: The mean walk time improved from 383 s (95% CI: 368-399) prior to surgery to 351 s (95% CI: 330-372) by 6 years. The mean resting HR was 90 beats per minute (bpm; 95% CI: 87-93) preoperatively and decreased to 80 bpm (95% CI: 76-84) by 6 years. The risk of any musculoskeletal pain decreased from 37.2% (95% CI: 25.5%-48.9%) to 11.0% (95% CI: 4.3%-17.6%) by 6 years. Mediation analysis revealed that the effect of time since surgery on walk time, resting HR, and HR recovery occurred through a weight-dependent mechanism. For posttest HR and HR difference, there was both a significant weight-dependent and weight-independent mechanism. The effect of surgery on the risk of musculoskeletal pain occurred through a weight-independent mechanism. CONCLUSIONS: Adolescents who underwent MBS experienced significant, durable improvement in mobility and pain, despite weight regain. Our models suggest that improvements may occur through a weight-independent mechanism.","journal":"Obesity","year":2025,"id":543877,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9382,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":369248,"name":"Todd Jenkins","orcid":"0000-0003-2669-3813","position":1,"is_corresponding":false},{"id":301419,"name":"Thomas H. Inge","orcid":"0000-0001-7782-1112","position":2,"is_corresponding":false},{"id":316721,"name":"Changchun Xie","orcid":"0000-0002-1843-4099","position":3,"is_corresponding":false},{"id":31468,"name":"Anita P. Courcoulas","orcid":"0000-0002-4973-7869","position":4,"is_corresponding":false},{"id":419346,"name":"Carroll M. Harmon","orcid":null,"position":5,"is_corresponding":false},{"id":301418,"name":"Michael A. Helmrath","orcid":"0000-0003-3112-7541","position":6,"is_corresponding":false},{"id":406167,"name":"Stephanie Sisley","orcid":"0000-0003-2900-7014","position":7,"is_corresponding":false},{"id":774666,"name":"Marc P. Michalsky","orcid":"0000-0002-7119-3634","position":8,"is_corresponding":false},{"id":376314,"name":"Justin R. Ryder","orcid":"0000-0002-7506-9497","position":9,"is_corresponding":false},{"id":414537,"name":"Neil Thivalapill","orcid":"0000-0003-3398-6710","position":0,"is_corresponding":true}],"reference_count":25,"raw_metadata":null,"created_at":"2026-07-19T02:53:08.338070Z","pmid":"40259728","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}