{"doi":"10.1002/oby.23562","title":"Effect of time‐restricted eating on sex hormone levels in premenopausal and postmenopausal females","abstract":"OBJECTIVE: Concerns have been raised regarding the impact of time-restricted eating (TRE) on sex hormones in females. This study examined how TRE affects sex steroids in premenopausal and postmenopausal females. METHODS: This is a secondary analysis of an 8-week TRE study (4- to 6-hour eating window) conducted in adults with obesity. Men and perimenopausal females were excluded. Females were classified into two groups based on menstrual status: premenopausal (n = 12) or postmenopausal (n = 11). RESULTS: After 8 weeks, body weight decreased in premenopausal females (-3% ± 2%) and postmenopausal females (-4% ± 2%) (main effect of time, p < 0.001), with no difference between groups (no group × time interaction). Circulating levels of testosterone, androstenedione, and sex hormone binding globulin (SHBG) did not change in either group (no group × time interaction). Dehydroepiandrosterone (DHEA) concentrations decreased (p < 0.05) in premenopausal (-14% ± 32%) and postmenopausal females (-13% ± 34%; main effect of time, p = 0.03), with no difference between groups. Estradiol, estrone, and progesterone were measured only in postmenopausal females, and they remained unchanged. CONCLUSIONS: In premenopausal females, androgens and SHBG remained unchanged during TRE, whereas DHEA decreased. In postmenopausal females, estrogens, progesterone, androgens, and SHBG did not change, but DHEA was reduced.","journal":"Obesity","year":2022,"id":257952,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":18,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7416,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":908876,"name":"Rand T. Akasheh","orcid":"0000-0002-0018-0342","position":1,"is_corresponding":false},{"id":225430,"name":"Sofia Cienfuegos","orcid":"0000-0002-2225-527X","position":2,"is_corresponding":false},{"id":408231,"name":"Aparna Ankireddy","orcid":null,"position":3,"is_corresponding":false},{"id":225431,"name":"Kelsey Gabel","orcid":"0000-0003-4613-8892","position":4,"is_corresponding":false},{"id":225433,"name":"Mark Ezpeleta","orcid":"0000-0002-0746-2414","position":5,"is_corresponding":false},{"id":225436,"name":"Shuhao Lin","orcid":"0000-0002-7982-746X","position":6,"is_corresponding":false},{"id":408229,"name":"Chandra Mohan Tamatam","orcid":null,"position":7,"is_corresponding":false},{"id":407355,"name":"Sekhar P. Reddy","orcid":"0000-0001-5027-9175","position":8,"is_corresponding":false},{"id":232382,"name":"Bonnie Spring","orcid":"0000-0003-0692-9868","position":9,"is_corresponding":false},{"id":286164,"name":"Seema A. Khan","orcid":"0000-0002-6307-2023","position":10,"is_corresponding":false},{"id":225438,"name":"Krista A Varady","orcid":"0000-0002-9279-9934","position":11,"is_corresponding":false},{"id":225432,"name":"Faiza Kalam","orcid":"0000-0003-4326-4009","position":0,"is_corresponding":true}],"reference_count":29,"raw_metadata":null,"created_at":"2026-07-19T00:25:38.634785Z","pmid":"36203273","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}