{"doi":"10.1002/oby.23420","title":"Early time‐restricted eating compared with daily caloric restriction: A randomized trial in adults with obesity","abstract":"<jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>This trial aimed to evaluate the acceptability and efficacy of early time‐restricted eating plus daily caloric restriction (E‐TRE+DCR) compared with DCR alone within a behavioral weight‐loss intervention.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Participants (<jats:italic>n</jats:italic> = 81, 69 women, mean [SD] age: 38.0 [7.8] years, BMI: 34.1 [5.7] kg/m<jats:sup>2</jats:sup>) were randomized to E‐TRE (10‐hour eating window starting within 3 hours of waking) plus DCR or DCR alone (~35% DCR) for 39 weeks. The primary outcome was body weight (measured with digital scale) at week 12. Secondary outcomes measured at week 12 included hemoglobin A1c, lipids, energy intake (photographic food records), physical activity (accelerometry), dietary adherence (questionnaires), and body composition (dual‐energy x‐ray absorptiometry). Weight and body composition were also assessed at week 39.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mean [SD] weight loss was not different between groups at week 12 (E‐TRE+DCR: −6.2 [4.1] kg vs. DCR: −5.1 [3.2] kg) or at week 39 (E‐TRE: −4.9 [5.3] kg vs. DCR: −4.3 [5.3] kg). There were no between‐group differences in changes in body composition, dietary adherence, energy intake, physical activity, hemoglobin A1c, or lipids at week 12.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>E‐TRE+DCR was found to be an acceptable dietary strategy, resulting in similar levels of adherence and weight loss compared with DCR alone.</jats:p></jats:sec>","journal":"Obesity","year":2022,"id":611782,"datarank":0.6749714505495399,"base_score":4.499809670330265,"endowment":4.499809670330265,"self_citation_contribution":0.6749714505495399,"citation_network_contribution":0.0,"self_endowment_contribution":0.6749714505495399,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":89,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":674228,"name":"Adnin Zaman","orcid":"0000-0002-6884-7748","position":1,"is_corresponding":false},{"id":1574787,"name":"Kelsey J. Sloggett","orcid":null,"position":2,"is_corresponding":false},{"id":1574788,"name":"Sheila Steinke","orcid":null,"position":3,"is_corresponding":false},{"id":1141338,"name":"Laura Grau","orcid":"0009-0001-3395-675X","position":4,"is_corresponding":false},{"id":661644,"name":"Victoria A. Catenacci","orcid":"0000-0001-9723-3748","position":5,"is_corresponding":false},{"id":1574789,"name":"Marc‐Andre Cornier","orcid":null,"position":6,"is_corresponding":false},{"id":300735,"name":"Corey A. Rynders","orcid":"0000-0001-5767-6261","position":7,"is_corresponding":false},{"id":321351,"name":"Elizabeth A. Thomas","orcid":"0000-0003-1137-6516","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Early time‐restricted eating compared with daily caloric restriction: A randomized trial in adults with obesity","abstract":"<jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>This trial aimed to evaluate the acceptability and efficacy of early time‐restricted eating plus daily caloric restriction (E‐TRE+DCR) compared with DCR alone within a behavioral weight‐loss intervention.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Participants (<jats:italic>n</jats:italic> = 81, 69 women, mean [SD] age: 38.0 [7.8] years, BMI: 34.1 [5.7] kg/m<jats:sup>2</jats:sup>) were randomized to E‐TRE (10‐hour eating window starting within 3 hours of waking) plus DCR or DCR alone (~35% DCR) for 39 weeks. The primary outcome was body weight (measured with digital scale) at week 12. Secondary outcomes measured at week 12 included hemoglobin A1c, lipids, energy intake (photographic food records), physical activity (accelerometry), dietary adherence (questionnaires), and body composition (dual‐energy x‐ray absorptiometry). Weight and body composition were also assessed at week 39.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mean [SD] weight loss was not different between groups at week 12 (E‐TRE+DCR: −6.2 [4.1] kg vs. DCR: −5.1 [3.2] kg) or at week 39 (E‐TRE: −4.9 [5.3] kg vs. DCR: −4.3 [5.3] kg). There were no between‐group differences in changes in body composition, dietary adherence, energy intake, physical activity, hemoglobin A1c, or lipids at week 12.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>E‐TRE+DCR was found to be an acceptable dietary strategy, resulting in similar levels of adherence and weight loss compared with DCR alone.</jats:p></jats:sec>","is_dataset_classified":null,"base_score":4.499809670330265,"endowment":4.499809670330265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"35470974","pmcid":"PMC9046980","openalex_id":"https://openalex.org/W4224936480","authors":[],"funders":[{"funder_name":"Doris Duke Charitable Foundation","grant_id":"2015212","title":null},{"funder_name":"National Center for Research Resources","grant_id":"UL 1 RR025780","title":null},{"funder_name":"National Institute of Diabetes and Digestive and Kidney Diseases","grant_id":"K01 DK113063","title":null},{"funder_name":"National Institute of Diabetes and Digestive and Kidney Diseases","grant_id":"R21DK117499","title":null},{"funder_name":"National Center for Advancing Translational Sciences","grant_id":"KL2TR002534","title":null},{"funder_name":"NIDDK NIH HHS","grant_id":"F32 DK123878","title":null},{"funder_name":"NIDDK NIH HHS","grant_id":"P30 DK048520","title":null},{"funder_name":"National Institutes of Health","grant_id":"1KL2TR002534-01","title":"Institutional Career Development Core"},{"funder_name":"National Institutes of Health","grant_id":"3UL1RR025780-02S2","title":"Colorado Clinical and Translational Science Institute (UL1)"},{"funder_name":"National Institutes of Health","grant_id":"5R21DK117499-02","title":"Time Restricted Feeding as a Weight Loss Intervention in Overweight and Obese Adults"},{"funder_name":"National Institutes of Health","grant_id":"1K01DK113063-01","title":"Time restricted feeding and metabolic rhythms in humans"}],"total_grants":11,"fwci":8.5761,"citation_percentile":0.98682925,"influential_citations":0,"citation_trend":[{"year":2022,"count":15},{"year":2023,"count":16},{"year":2024,"count":30},{"year":2025,"count":17},{"year":2026,"count":10}],"oa_status":"green","license":"Wiley Online Library User Agreement","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9046980","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9046980","host_type":"repository"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/oby.23420","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/oby.23420","host_type":"publisher"},{"url":"https://doi.org/10.1002/oby.23420","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/35470974","host_type":"repository"}],"fields_of_study":["Dietary Effects on Health","Circadian rhythm and melatonin","Enhanced Recovery After Surgery","0301 basic medicine","0303 health sciences","03 medical and health sciences","Adult","Caloric Restriction","Energy Intake","Female","Glycated Hemoglobin","Humans","Lipids","Male","Obesity","Weight Loss"],"mesh_terms":["Adult","Energy Intake","Female","Glycated Hemoglobin","Humans","Lipids","Male","Obesity","Weight Loss","Caloric Restriction"],"keywords":["Caloric theory","Medicine","Obesity","Randomized controlled trial","Caloric intake","Gerontology","Internal medicine","Adult","Glycated Hemoglobin","Male","Lipids","Weight Loss","Humans","Female","Energy Intake","Caloric Restriction"],"sdg_mappings":[{"sdg_number":2,"sdg_label":"2. 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