{"doi":"10.1002/nbm.5017","title":"Quality assessment of routine brain imaging at 0.55 T: initial experience in a clinical workflow","abstract":"<jats:title>Abstract</jats:title><jats:p>The purpose of this study was to assess the quality of clinical brain imaging in healthy subjects and patients on an FDA‐approved commercial 0.55 T MRI scanner, and to provide information about the feasibility of using this scanner in a clinical workflow. In this IRB‐approved study, brain examinations on the scanner were prospectively performed in 10 healthy subjects (February–April 2022) and retrospectively derived from 44 patients (February–July 2022). Images collected using the following pulse sequences were available for assessment: axial DWI (diffusion‐weighted imaging), apparent diffusion coefficient maps, 2D axial fluid‐attenuated inversion recovery images, axial susceptibility‐weighted images (both magnitude and phase), sagittal <jats:italic>T</jats:italic><jats:sub>1</jats:sub>‐weighted (T1w) Sampling Perfection with Application Optimized Contrast images, sagittal T1w MPRAGE (magnetization prepared rapid gradient echo) with contrast enhancement, axial T1w turbo spin echo (TSE) with and without contrast enhancement, and axial <jats:italic>T</jats:italic><jats:sub>2</jats:sub>‐weighted TSE. Two readers retrospectively and independently evaluated image quality and specific anatomical features in a blinded fashion on a four‐point Likert scale, with a score of 1 being unacceptable and 4 being excellent, and determined the ability to answer the clinical question in patients. For each category of image sequences, the mean, standard deviation, and percentage of unacceptable quality images (&lt;2) were calculated. Acceptable (rating ≥ 2) image quality was achieved at 0.55 T in all sequences for patients and 85% of the sequences for healthy subjects. Radiologists were able to answer the clinical question in all patients scanned. In total, 50% of the sequences used in patients and about 60% of the sequences used in healthy subjects exhibited good (rating ≥ 3) image quality. Based on these findings, we conclude that diagnostic quality clinical brain images can be successfully collected on this commercial 0.55 T scanner, indicating that the routine brain imaging protocol may be deployed on this system in the clinical workflow.</jats:p>","journal":"NMR in Biomedicine","year":2024,"id":647565,"datarank":0.528027426403753,"base_score":2.8903717578961645,"endowment":2.8903717578961645,"self_citation_contribution":0.4335557636844247,"citation_network_contribution":0.09447166271932823,"self_endowment_contribution":0.4335557636844247,"citer_contribution":0.09447166271932823,"corpus_percentile":null,"corpus_rank":null,"citation_count":17,"citer_count":9,"citers_with_citation_signal":4,"citers_with_endowment":4,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":950222,"name":"Shruti Mishra","orcid":"0000-0002-9487-5531","position":1,"is_corresponding":false},{"id":1483248,"name":"Jacob Richardson","orcid":"0000-0001-8138-7582","position":2,"is_corresponding":false},{"id":1077943,"name":"Maria Masotti","orcid":"0000-0001-6591-3212","position":3,"is_corresponding":false},{"id":690555,"name":"Ryo Kurokawa","orcid":"0000-0002-1186-8900","position":4,"is_corresponding":false},{"id":1571530,"name":"Mariko Kurokawa","orcid":"0000-0002-3907-9188","position":5,"is_corresponding":false},{"id":1687218,"name":"Pedro Itriago‐Leon","orcid":null,"position":6,"is_corresponding":false},{"id":354257,"name":"Vikas Gulani","orcid":"0000-0003-0889-5999","position":7,"is_corresponding":false},{"id":1687220,"name":"Brendan McCracken","orcid":null,"position":8,"is_corresponding":false},{"id":777321,"name":"Katherine Wright","orcid":"0000-0001-5967-8156","position":9,"is_corresponding":false},{"id":702052,"name":"Hero K. Hussain","orcid":"0000-0003-3236-0652","position":10,"is_corresponding":false},{"id":160934,"name":"Toshio Moritani","orcid":null,"position":11,"is_corresponding":false},{"id":325704,"name":"Nicole Seiberlich","orcid":"0000-0002-8356-5407","position":12,"is_corresponding":false},{"id":1276417,"name":"Anna Lavrova","orcid":"0009-0001-7521-7082","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Quality assessment of routine brain imaging at 0.55 T: initial experience in a clinical workflow","abstract":"<jats:title>Abstract</jats:title><jats:p>The purpose of this study was to assess the quality of clinical brain imaging in healthy subjects and patients on an FDA‐approved commercial 0.55 T MRI scanner, and to provide information about the feasibility of using this scanner in a clinical workflow. In this IRB‐approved study, brain examinations on the scanner were prospectively performed in 10 healthy subjects (February–April 2022) and retrospectively derived from 44 patients (February–July 2022). Images collected using the following pulse sequences were available for assessment: axial DWI (diffusion‐weighted imaging), apparent diffusion coefficient maps, 2D axial fluid‐attenuated inversion recovery images, axial susceptibility‐weighted images (both magnitude and phase), sagittal <jats:italic>T</jats:italic><jats:sub>1</jats:sub>‐weighted (T1w) Sampling Perfection with Application Optimized Contrast images, sagittal T1w MPRAGE (magnetization prepared rapid gradient echo) with contrast enhancement, axial T1w turbo spin echo (TSE) with and without contrast enhancement, and axial <jats:italic>T</jats:italic><jats:sub>2</jats:sub>‐weighted TSE. 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Based on these findings, we conclude that diagnostic quality clinical brain images can be successfully collected on this commercial 0.55 T scanner, indicating that the routine brain imaging protocol may be deployed on this system in the clinical workflow.</jats:p>","is_dataset_classified":null,"base_score":2.8903717578961645,"endowment":2.8903717578961645,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"37654047","pmcid":null,"openalex_id":"https://openalex.org/W4386347066","authors":[],"funders":[{"funder_name":"Siemens Healthineers","grant_id":"","title":null},{"funder_name":"Siemens Healthineers","grant_id":"","title":null}],"total_grants":2,"fwci":3.5342,"citation_percentile":0.93219404,"influential_citations":0,"citation_trend":[{"year":2024,"count":3},{"year":2025,"count":11},{"year":2026,"count":3}],"oa_status":"hybrid","license":"cc-by-nc-nd","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/nbm.5017","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/nbm.5017","host_type":"publisher"},{"url":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/pdf/10.1002/nbm.5017","host_type":"publisher"},{"url":"https://doi.org/10.1002/nbm.5017","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/37654047","host_type":"repository"},{"url":"https://archive.ismrm.org/2019/1214.html","host_type":"repository"}],"fields_of_study":["Advanced MRI Techniques and Applications","Advanced Neuroimaging Techniques and Applications","MRI in cancer diagnosis","Humans","Workflow","Brain","Female","Male","Adult","Middle Aged","Aged","Magnetic Resonance Imaging","Young Adult"],"mesh_terms":["Adult","Aged","Brain","Female","Humans","Magnetic Resonance Imaging","Male","Middle Aged","Young Adult","Workflow"],"keywords":["Image quality","Medicine","Sagittal plane","Scanner","Nuclear medicine","Diffusion MRI","Magnetic resonance imaging","Radiology","Artificial intelligence","Computer science","Image (mathematics)","Brain Mri","Accessible Mri","0.55 T Mri","Low‐field Mri","Low‐cost Mri"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T01:14:12.538581Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}