{"doi":"10.1002/mrm.30364","title":"Simultaneous multi‐slice cardiac real‐time <scp>MRI</scp> at 0. <scp>55T</scp>","abstract":"PURPOSE: To determine the feasibility of simultaneous multi-slice (SMS) real-time MRI (RT-MRI) at 0.55T for the evaluation of cardiac function. METHODS: Cardiac CINE MRI is routinely used to evaluate left-ventricular (LV) function. The standard is sequential multi-slice balanced SSFP (bSSFP) over a stack of short-axis slices using electrocardiogram (ECG) gating and breath-holds. SMS has been used in CINE imaging to reduce the number of breath-holds by a factor of 2-4 at 1.5T, 3T, and recently at 0.55T. This work aims to determine if SMS is similarly effective in the RT-MRI evaluation of cardiac function. We used an SMS bSSFP pulse sequence with golden-angle spirals at 0.55T with an SMS factor of three. We cover the LV with three acquisitions for SMS, and nine for single-band (SB). Imaging was performed on 9 healthy volunteers and 1 patient with myocardial fibrosis and sternal wires. A spatio-temporal constrained reconstruction is used, with regularization parameters selected by a board-certified cardiologist. Images were quantitatively analyzed with a normalized contrast and an Edge Sharpness (ES) score. RESULTS: There was a statistically significant 2-fold difference in contrast between SMS and SB and no significant difference in ES score. The contrast for SMS and SB were 13.38/29.05 at mid-diastole and 10.79/22.26 at end-systole; the ES scores for SMS and SB were 1.77/1.83 at mid-diastole and 1.50/1.72 at end-systole. CONCLUSIONS: SMS cardiac RT-MRI at 0.55T is feasible and provides sufficient blood-myocardium contrast to evaluate LV function in three slices simultaneously without any gating or periodic motion assumptions.","journal":"Magnetic Resonance in Medicine","year":2024,"id":443625,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9512,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":443421,"name":"Parveen K. Garg","orcid":"0000-0002-6482-2711","position":1,"is_corresponding":false},{"id":522004,"name":"Steven Cen","orcid":"0000-0002-7859-8909","position":2,"is_corresponding":false},{"id":280605,"name":"Krishna S. Nayak","orcid":"0000-0001-5735-3550","position":3,"is_corresponding":false},{"id":478980,"name":"Ye Tian","orcid":"0000-0002-8559-4404","position":4,"is_corresponding":false},{"id":1258241,"name":"Ecrin Yağız","orcid":"0000-0001-8113-2192","position":0,"is_corresponding":true}],"reference_count":44,"raw_metadata":null,"created_at":"2026-07-19T02:01:29.001453Z","pmid":"39506513","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}