{"doi":"10.1002/mp.17643","title":"A magnetic field compatible readout circuit for enhanced coincidence time resolution in BGO Cherenkov radiation–based TOF‐PET detectors","abstract":"Abstract Background Developing time‐of‐flight positron emission tomography/magnetic resonance imaging (TOF‐PET/MRI) detectors that exploit prompt Cherenkov photons from bismuth germanate (BGO) crystals for estimating 511 keV photon arrival time. Purpose To present a low‐noise, high‐speed electronic readout circuit design for BGO‐based TOF‐PET detectors that achieves enhanced coincidence time resolution (CTR) in presence of a strong magnetic field. Methods The CTR of a BGO‐based TOF‐PET test detector employing a high‐speed, low‐noise electronic readout chain was evaluated in a strong magnetic field produced by a permanent magnet placed directly on top of the circuit. For these experiments, which exploit Cherenkov radiation for precise measurement of annihilation photon time arrival time difference, a point source of 22 Na was positioned between a pair of 3 × 3 × 15 mm 3 polished BGO crystals wrapped in Teflon tape and optically coupled to 3 × 3 mm 2 ultra‐violet (UV)‐sensitive silicon photomultipliers (SiPMs). Results By incorporating both Cherenkov (prompt) and standard (slow) luminescence components, 283 ± 8 ps and 275 ± 10 ps full‐width‐half‐maximum (FWHM) CTR were achieved without and with the permanent magnet present, respectfully. These values improved to 236 ± 4 ps and 216 ± 17 ps FWHM when only the Cherenkov components of the timing signal (events with the fastest rise time) were considered. Conclusions Results indicate we have designed a high‐performance readout circuit that achieves significantly the same CTR in BGO with or without a strong magnetic field present. This further demonstrates that UV SiPMs can effectively operate in a strong magnetic field while remaining highly advantageous for detecting Cherenkov radiation, thus highlighting their potential to be used in BGO‐based TOF‐PET/MRI scanners.","journal":"Medical Physics","year":2025,"id":551428,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.946,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":568963,"name":"Joshua W. Cates","orcid":"0000-0002-5649-8691","position":1,"is_corresponding":false},{"id":490894,"name":"Craig S. Levin","orcid":"0000-0002-4575-5074","position":2,"is_corresponding":false},{"id":568962,"name":"Shirin Pourashraf","orcid":"0000-0001-8013-1171","position":0,"is_corresponding":true}],"reference_count":12,"raw_metadata":null,"created_at":"2026-07-19T02:54:25.065895Z","pmid":"39887725","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}