{"doi":"10.1002/mp.15411","title":"The detective quantum efficiency of cadmium telluride photon‐counting x‐ray detectors in breast imaging applications","abstract":"<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>In breast imaging applications, cadmium telluride (CdTe) photon counting x‐ray detectors (PCDs) may reduce radiation dose and enable single‐shot multi‐energy x‐ray imaging. The purpose of this work is to determine the upper limits of the detective quantum efficiency (DQE) of CdTe PCDs for x‐ray mammography and to compare them with the published DQEs of energy‐integrating detectors (EIDs) and other PCDs.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We calibrated and validated a Monte Carlo (MC) model of the DQE of CdTe PCDs using an XCounter CdTe PCD. Our model accounted for charge sharing, electronic noise, and charge summation logic. We used a 28 kVp Mo/Mo spectrum hardened by 3.9 cm of Lucite to optimize the detector thickness and energy threshold for pixel sizes of 50, 85, and 100 <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0001.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0001\"/>m with and without inter‐pixel charge summation logic. The figure of merit used for optimization was the integral of the DQE, which is equivalent to the detectability index for a delta function task function, which represents a high‐frequency task.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>For an electronic noise level equal to that of the XCounter, the optimal DQE(0) without charge summing was 0.74. Charge summing for charge‐sharing correction reduced DQE(0) by 14% due to an increase in electronic noise. Reducing the electronic noise to ∼0.5 keV per pixel in combination with charge summing resulted in DQE(0) <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0002.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0002\"/>0.78 for 85 <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0003.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0003\"/>m pixels, which is approximately equal to that of <jats:italic>a</jats:italic>‐Se and slot‐scanning silicon‐strip PCDs. At higher spatial frequencies, and for matched pixel sizes, the DQE was inferior to that of <jats:italic>a</jats:italic>‐Se EIDs and superior to that of slot‐scanning silicon‐strip PCDs in the scan direction but inferior in the slit direction.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>(1) CdTe PCDs have the potential to provide a zero‐frequency DQE equal to that of <jats:italic>a</jats:italic>‐Se EIDs and slot‐scanning silicon‐strip PCDs, but this will require electronic noise levels ∼0.5 keV per pixel. (2) At mid‐to‐high spatial frequencies the DQE of CdTe PCDs may be (a) inferior to that of <jats:italic>a</jats:italic>‐Se EIDs and slot‐scanning silicon‐strip PCDs in the slit direction, and (b) superior to slot‐scanning silicon‐strip PCDs in the scan direction.</jats:p></jats:sec>","journal":"Medical Physics","year":2022,"id":655062,"datarank":0.3453877639491069,"base_score":2.302585092994046,"endowment":2.302585092994046,"self_citation_contribution":0.3453877639491069,"citation_network_contribution":0.0,"self_endowment_contribution":0.3453877639491069,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1709809,"name":"Jesse Tanguay","orcid":null,"position":1,"is_corresponding":false},{"id":1709808,"name":"James A. Day","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The detective quantum efficiency of cadmium telluride photon‐counting x‐ray detectors in breast imaging applications","abstract":"<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>In breast imaging applications, cadmium telluride (CdTe) photon counting x‐ray detectors (PCDs) may reduce radiation dose and enable single‐shot multi‐energy x‐ray imaging. The purpose of this work is to determine the upper limits of the detective quantum efficiency (DQE) of CdTe PCDs for x‐ray mammography and to compare them with the published DQEs of energy‐integrating detectors (EIDs) and other PCDs.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We calibrated and validated a Monte Carlo (MC) model of the DQE of CdTe PCDs using an XCounter CdTe PCD. Our model accounted for charge sharing, electronic noise, and charge summation logic. We used a 28 kVp Mo/Mo spectrum hardened by 3.9 cm of Lucite to optimize the detector thickness and energy threshold for pixel sizes of 50, 85, and 100 <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0001.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0001\"/>m with and without inter‐pixel charge summation logic. The figure of merit used for optimization was the integral of the DQE, which is equivalent to the detectability index for a delta function task function, which represents a high‐frequency task.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>For an electronic noise level equal to that of the XCounter, the optimal DQE(0) without charge summing was 0.74. Charge summing for charge‐sharing correction reduced DQE(0) by 14% due to an increase in electronic noise. Reducing the electronic noise to ∼0.5 keV per pixel in combination with charge summing resulted in DQE(0) <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0002.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0002\"/>0.78 for 85 <jats:inline-graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"graphic/mp15411-math-0003.png\" xlink:title=\"urn:x-wiley:00942405:media:mp15411:mp15411-math-0003\"/>m pixels, which is approximately equal to that of <jats:italic>a</jats:italic>‐Se and slot‐scanning silicon‐strip PCDs. At higher spatial frequencies, and for matched pixel sizes, the DQE was inferior to that of <jats:italic>a</jats:italic>‐Se EIDs and superior to that of slot‐scanning silicon‐strip PCDs in the scan direction but inferior in the slit direction.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>(1) CdTe PCDs have the potential to provide a zero‐frequency DQE equal to that of <jats:italic>a</jats:italic>‐Se EIDs and slot‐scanning silicon‐strip PCDs, but this will require electronic noise levels ∼0.5 keV per pixel. (2) At mid‐to‐high spatial frequencies the DQE of CdTe PCDs may be (a) inferior to that of <jats:italic>a</jats:italic>‐Se EIDs and slot‐scanning silicon‐strip PCDs in the slit direction, and (b) superior to slot‐scanning silicon‐strip PCDs in the scan direction.</jats:p></jats:sec>","is_dataset_classified":null,"base_score":2.302585092994046,"endowment":2.302585092994046,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34905627","pmcid":null,"openalex_id":"https://openalex.org/W4200038152","authors":[],"funders":[{"funder_name":"Natural Sciences and Engineering Research Council of Canada","grant_id":"unidentified","title":"unidentified"},{"funder_name":"Canadian Foundation for Innovation (CFI) and the Ontario Research Fund (ORF)","grant_id":"","title":null},{"funder_name":"Natural Sciences and Engineering Research Council of Canada","grant_id":"","title":null},{"funder_name":"Natural Sciences and Engineering Research Council of Canada","grant_id":"","title":null},{"funder_name":"Canadian Foundation for Innovation (CFI) and the Ontario Research Fund (ORF)","grant_id":"","title":null}],"total_grants":5,"fwci":0.6524,"citation_percentile":0.70300947,"influential_citations":0,"citation_trend":[{"year":2023,"count":2},{"year":2024,"count":3},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"closed","license":"Wiley Online Library User Agreement","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/mp.15411","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/mp.15411","host_type":"publisher"},{"url":"https://aapm.onlinelibrary.wiley.com/doi/pdf/10.1002/mp.15411","host_type":"publisher"},{"url":"https://doi.org/10.1002/mp.15411","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34905627","host_type":"repository"}],"fields_of_study":["Digital Radiography and Breast Imaging","Advanced X-ray and CT Imaging","Radiation Shielding Materials Analysis","03 medical and health sciences","0302 clinical medicine","Cadmium Compounds","Quantum Dots","Tellurium","X-Rays"],"mesh_terms":["Tellurium","X-Rays","Cadmium Compounds","Quantum Dots"],"keywords":["Detective quantum efficiency","Charge sharing","Physics","Optics","Detector","X-ray detector","Photon","Figure of merit","Noise (video)","Photon counting","Dot pitch","Cadmium telluride photovoltaics","Pixel","Optoelectronics","Image quality","Computer science","Image (mathematics)","Artificial intelligence","Monte Carlo","Breast Imaging","mammography","Cadmium Telluride","X-Rays","Quantum Dots","Cadmium Compounds","Tellurium"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Affordable and clean energy"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-11T09:29:56.629317Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}