{"doi":"10.1002/mnfr.202170031","title":"Front Cover: Methylglyoxal‐Lysine Dimer, an Advanced Glycation End Product, Induces Inflammation via Interaction with RAGE in Mesangial Cells","abstract":null,"journal":"Molecular Nutrition & Food Research","year":2021,"id":672566,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1757234,"name":"Min Ji Gu","orcid":null,"position":1,"is_corresponding":false},{"id":379235,"name":"Jee‐Young Lee","orcid":"0000-0002-9120-2075","position":2,"is_corresponding":false},{"id":1757235,"name":"Seungju Lee","orcid":null,"position":3,"is_corresponding":false},{"id":1757236,"name":"Yoonsook Kim","orcid":null,"position":4,"is_corresponding":false},{"id":1132527,"name":"Sang Keun Ha","orcid":"0000-0002-3329-2279","position":5,"is_corresponding":false},{"id":1757233,"name":"Hee‐Weon Lee","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Front Cover: Methylglyoxal‐Lysine Dimer, an Advanced Glycation End Product, Induces Inflammation via Interaction with RAGE in Mesangial Cells","abstract":"Mol. Nutr. Food Res. 2021, 65, 2000799 DOI: 10.1002/mnfr.202000799 Methylglyoxal-lysine dimer, a typical advanced glycation end product, contributes to inflammatory responses during renal disorder. The interaction of Methylglyoxal-lysine dimer (MOLD) and receptor of advanced glycation end products (RAGE) causes reactive oxygen species (ROS) production and mitochondrial dysfunction in mesangial cells. Further, the NF-kB and PI3K/AKT signaling pathways triggered by ROS exacerbate the inflammatory responses in MOLD-induced renal damages. This is reported by Sang Keun Ha and co-workes in article number 2000799.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19965766","pmcid":null,"openalex_id":"https://openalex.org/W4205678163","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/mnfr.202170031","host_type":"publisher"},{"url":"https://doi.org/10.1002/mnfr.202170031","host_type":"journal"}],"fields_of_study":["Advanced Glycation End Products research"],"mesh_terms":[],"keywords":["Methylglyoxal","Glycation","Advanced glycation end-product","Mesangial cell","Rage (emotion)","Chemistry","Reactive oxygen species","Lysine","Lactoylglutathione lyase","Inflammation","Biochemistry","Receptor","Cell biology","Immunology","Biology","Amino acid","Enzyme"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-16T09:35:49.286320Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}