{"doi":"10.1002/mds.30202","title":"Validation of the International Parkinson and Movement Disorder Society Non‐Motor Symptoms Questionnaire (<scp>MDS</scp>‐<scp>NMS</scp>‐Q)","abstract":"BACKGROUND: The Movement Disorder Society Non-Motor Rating Scale (MDS-NMS) assesses severity and frequency of non-motor symptoms (NMS) in Parkinson's disease (PD) and is rater-administered. The MDS-NMS Questionnaire (MDS-NMS-Q), developed as a briefer (i.e., assessing symptom severity only), self-completed version of the MDS-NMS, is also a 13-domain, 52-symptom instrument with a separate non-motor fluctuations (NMFs) section. OBJECTIVE: The goal was to validate the MDS-NMS-Q versus the MDS-NMS. METHODS: A cross-sectional, multi-site, international study was conducted with idiopathic PD patients. After completing the self-administered MDS-NMS-Q unsupervised, patients were assessed with the rater-administered MDS-NMS. RESULTS: The cohort consisted of 199 PD patients (mean age [±standard deviation (SD)] = 67.19 [±9.95] years; mean age at PD diagnosis [±SD] = 59.27 [±9.54] years); median Hoehn and Yahr stage = 2. Data quality was satisfactory for all 13 MDS-NMS-Q domains. There were no floor or ceiling effects for the total score; individual domains had no appreciable ceiling effects, but variable floor effects (5.0%-71.4%). Internal consistency for most domains was satisfactory, except for the impulse control domain (Cronbach's α ≥0.75 for 10/13 domains). Correlation and concordance between MDS-NMS-Q and MDS-NMS total scores were high (Spearman rank correlation coefficient = 0.86; Kendall's coefficient of concordance = 0.93). CONCLUSIONS: The MDS-NMS-Q has a strong association and concordance with the MDS-NMS at the total score and domain level. This indicates that the MDS-NMS-Q, allowing self-completion and focusing only on symptom severity, is an acceptable alternative to rater administration assessing both severity and frequency. © 2025 International Parkinson and Movement Disorder Society.","journal":"Movement Disorders","year":2025,"id":530058,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6443,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":656916,"name":"К. Ray Chaudhuri","orcid":"0000-0003-2815-0505","position":1,"is_corresponding":false},{"id":92196,"name":"Anette Schrag","orcid":"0000-0002-9872-6680","position":2,"is_corresponding":false},{"id":92200,"name":"Pablo Martínez‐Martín","orcid":"0000-0003-0837-5280","position":3,"is_corresponding":false},{"id":1409399,"name":"Alexandra Rizos","orcid":"0000-0002-0935-9111","position":4,"is_corresponding":false},{"id":537802,"name":"Eugenia Mamikonyan","orcid":"0009-0007-7414-9480","position":5,"is_corresponding":false},{"id":1203492,"name":"Julia Gallagher","orcid":null,"position":6,"is_corresponding":false},{"id":1409869,"name":"Izabelle Schoen","orcid":null,"position":7,"is_corresponding":false},{"id":1409400,"name":"Juliet Staunton","orcid":"0009-0009-9535-1199","position":8,"is_corresponding":false},{"id":446095,"name":"Marta Fernandes","orcid":"0000-0002-7203-2832","position":9,"is_corresponding":false},{"id":1409401,"name":"Carmen Rodríguez‐Blázquez","orcid":"0000-0003-3829-0675","position":10,"is_corresponding":false},{"id":80309,"name":"Daniel Weintraub","orcid":"0000-0003-0633-7168","position":0,"is_corresponding":true}],"reference_count":32,"raw_metadata":null,"created_at":"2026-07-19T02:51:01.235017Z","pmid":"40251003","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}