{"doi":"10.1002/lary.31018","title":"Palate shape is associated with Unilateral Hypoglossal Nerve Stimulation Outcomes","abstract":"OBJECTIVE: The aim was to determine the potential association between palate shape and unilateral hypoglossal nerve stimulation (HNS) outcomes. METHODS: Preoperative drug-induced sleep endoscopy (DISE) videos were reviewed and scored by 3 blinded reviewers to determine airway narrowing at the hard-soft palate junction (HP), soft palate genu, and inferior velum, as described by Woodson (2014). Scoring was as follows: 1-open airway, 2-narrow, 3-severe narrowing. Overall palate shape (oblique, intermediate, or vertical) was determined based on prior criteria. Successful surgical treatment was defined by the HNS titration polysomnogram as a reduction of ≥50% in the apnea-hypopnea index (AHI) to <15 events/h. RESULTS: . Overall success rate was 73%. Success rate was lower in patients with vertical palate shape compared with the other shapes (56% vs. 75%, p = 0.029). HP score 3 compared with scores 2 and 1 was associated with lower success rates (60% vs. 76%, p = 0.028), but genu and velum scores were not associated with outcomes. Patients with both HP score 3 and complete oropharyngeal lateral wall-related obstruction had notably worse outcomes (22% vs. 74%, p = 0.026). HP score 3 (OR 0.45, 95%CI 0.22-0.92) and vertical palate shape (OR 0.33, 95%CI 0.15-0.78) were independently associated with lower odds of surgical response after adjustment for DISE findings, age, gender, and BMI. CONCLUSION: Vertical palate shape and narrowing at the hard-soft palate junction are independently associated with lower HNS surgical success rates. LEVEL OF EVIDENCE: 3 Laryngoscope, 134:981-986, 2024.","journal":"The Laryngoscope","year":2023,"id":362791,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9284,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1116314,"name":"Abhay Sharma","orcid":"0000-0003-1306-1497","position":1,"is_corresponding":false},{"id":1116315,"name":"Emily A. Commesso","orcid":"0000-0002-0131-6977","position":2,"is_corresponding":false},{"id":1116316,"name":"B. Tucker Woodson","orcid":"0000-0003-2396-2926","position":3,"is_corresponding":false},{"id":811691,"name":"Phillip Huyett","orcid":"0000-0002-1951-3266","position":4,"is_corresponding":false},{"id":532254,"name":"David T. Kent","orcid":"0000-0001-8183-5269","position":5,"is_corresponding":false},{"id":1116317,"name":"Mark A. D׳Agostino","orcid":"0000-0001-5878-5670","position":6,"is_corresponding":false},{"id":1116792,"name":"Katherine K. Green","orcid":null,"position":7,"is_corresponding":false},{"id":1116318,"name":"Eric J. Kezirian","orcid":"0000-0003-3808-4521","position":8,"is_corresponding":false},{"id":1116313,"name":"Suraj Kedarisetty","orcid":"0000-0002-5276-5414","position":0,"is_corresponding":true}],"reference_count":18,"raw_metadata":null,"created_at":"2026-07-19T01:14:23.749325Z","pmid":"37672634","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}