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RNA shedding median duration was 14 days (IQR 8.0–21.0) for nasopharyngeal/throat (NPT) and 7 days (IQR 1.0–27.0) for feces— but 20 days (IQR 7.0–27.8) when excluding individuals positive at a single timepoint (25.2%). Among 17 NPT long shedders with FlowSA results, 12 (70.6%) demonstrated viable virus. NPT long shedding was independently positively associated with endocrine disease and chills. Fecal long shedding was independently inversely associated with age, female sex, and fatigue, but positively with vomiting. No associations with long‐term COVID‐19‐related complaints were observed. Finally, fecal long shedders demonstrated higher anti‐spike(S1) IgG levels over 18‐month follow‐up than non‐long shedders (<jats:italic>p</jats:italic> = 0.006). (Long) SARS‐CoV‐2 RNA shedding in NPT and feces associates with age and acute—but not prolonged—symptoms. The roles of prolonged infectious shedding and fecal shedding in transmission and immunity remain unclear.</jats:p>","journal":"Journal of Medical Virology","year":2024,"id":614119,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1582420,"name":"Imran A. 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(Long) SARS‐CoV‐2 RNA shedding in NPT and feces associates with age and acute—but not prolonged—symptoms. 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