{"doi":"10.1002/jmv.28042","title":"Clinical characteristics, outcomes, and seasonality of acute respiratory infection associated with single and codetected rhinovirus species among hospitalized children in Amman, Jordan","abstract":"Rhinovirus (RV)-specific surveillance studies in the Middle East are limited. Therefore, we aimed to study the clinical characteristics, outcomes, and seasonality of RV-associated acute respiratory infection among hospitalized young children in Jordan. We conducted a prospective viral surveillance study and enrolled children <2 years old admitted to a large public hospital in Amman, Jordan (2010-2013). Demographic and clinical data were collected by structured interviews and chart abstractions. Nasal and/or throat swabs were collected and tested for a panel of respiratory viruses, and RV genotyping and speciation was performed. At least one virus was detected in 2641/3168 children (83.4%). RV was the second most common virus detected (n = 1238; 46.9%) and was codetected with another respiratory virus in 730 cases (59.0%). Children with RV codetection were more likely than those with RV-only detection to have respiratory distress but had similar outcomes. RV-A accounted for about half of RV-positive cases (54.7%), while children with RV-C had a higher frequency of wheezing and reactive airway disease. RV was detected year-round and peaked during winter. In conclusion, though children with RV codetection had worse clinical findings, neither codetection nor species affected most clinical outcomes.","journal":"Journal of Medical Virology","year":2022,"id":286570,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9397,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":953210,"name":"Justin Z. Amarin","orcid":"0000-0002-4484-1077","position":1,"is_corresponding":false},{"id":308125,"name":"Danielle A. Rankin","orcid":"0000-0003-3018-3373","position":2,"is_corresponding":false},{"id":762260,"name":"Sean M. Bloos","orcid":"0000-0002-1044-4823","position":3,"is_corresponding":false},{"id":966327,"name":"Yanal Shawareb","orcid":null,"position":4,"is_corresponding":false},{"id":327400,"name":"Herdi Rahman","orcid":null,"position":5,"is_corresponding":false},{"id":308124,"name":"Zaid Haddadin","orcid":"0000-0001-6863-6185","position":6,"is_corresponding":false},{"id":328310,"name":"Leigh M. Howard","orcid":"0000-0003-4301-7235","position":7,"is_corresponding":false},{"id":308126,"name":"Varvara Probst","orcid":"0000-0003-4633-8552","position":8,"is_corresponding":false},{"id":965878,"name":"Randa Naffa","orcid":"0000-0001-5192-1799","position":9,"is_corresponding":false},{"id":480169,"name":"Monika Johnson","orcid":null,"position":10,"is_corresponding":false},{"id":682101,"name":"Sidney Lane","orcid":"0000-0001-7639-7911","position":11,"is_corresponding":false},{"id":966328,"name":"Amy J. Kinzler","orcid":null,"position":12,"is_corresponding":false},{"id":308127,"name":"Andrew J. Spieker","orcid":"0000-0002-0548-8311","position":13,"is_corresponding":false},{"id":384488,"name":"Samir Faouri","orcid":null,"position":14,"is_corresponding":false},{"id":383690,"name":"Asem Shehabi","orcid":"0000-0002-2628-6284","position":15,"is_corresponding":false},{"id":105611,"name":"James D. Chappell","orcid":"0000-0002-7382-7864","position":16,"is_corresponding":false},{"id":227058,"name":"Najwa Khuri‐Bulos","orcid":"0000-0003-3456-7374","position":17,"is_corresponding":false},{"id":236968,"name":"John V. Williams","orcid":"0000-0001-8377-5175","position":18,"is_corresponding":false},{"id":105913,"name":"Natasha Halasa","orcid":"0000-0002-6381-1826","position":19,"is_corresponding":false},{"id":389417,"name":"Rana Talj","orcid":null,"position":0,"is_corresponding":true}],"reference_count":40,"raw_metadata":null,"created_at":"2026-07-19T00:29:52.825777Z","pmid":"35918790","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}