{"doi":"10.1002/jmri.29541","title":"Self‐Gated Radial Free‐Breathing Liver <scp>MR</scp> Elastography: Assessment of Technical Performance in Children at <scp>3 T</scp>","abstract":"BACKGROUND: Conventional liver magnetic resonance elastography (MRE) requires breath-holding (BH) to avoid motion artifacts, which is challenging for children. While radial free-breathing (FB)-MRE is an alternative for quantifying liver stiffness (LS), previous methods had limitations of long scan times, acquiring two slices in 5 minutes, and not resolving motion during reconstruction. PURPOSE: To reduce FB-MRE scan time to 4 minutes for four slices and to investigate the impact of self-gated (SG) motion compensation on FB-MRE LS quantification in terms of agreement, intrasession repeatability, and technical quality compared to conventional BH-MRE. STUDY TYPE: Prospective. POPULATION: Twenty-six children without fibrosis (median age: 12.9 years, 15 females). FIELD STRENGTH/SEQUENCE: 3 T; Cartesian gradient-echo (GRE) BH-MRE, research application radial GRE FB-MRE. ASSESSMENT: Participants were scanned twice to measure repeatability, without moving the table or changing the participants' position. LS was measured in areas of the liver with numerical confidence ≥90%. Technical quality was examined using measurable liver area (%). STATISTICAL TESTS: Agreement of LS between BH-MRE and FB-MRE was evaluated using Bland-Altman analysis for SG acceptance rates of 40%, 60%, 80%, and 100%. LS repeatability was assessed using within-subject coefficient of variation (wCV). The differences in LS and measurable liver area were examined using Kruskal-Wallis and Wilcoxon signed-rank tests. P < 0.05 was considered significant. RESULTS: FB-MRE with 60% SG achieved the closest agreement with BH-MRE (mean difference 0.00 kPa). The LS ranged from 1.70 to 1.83 kPa with no significant differences between BH-MRE and FB-MRE with varying SG rates (P = 0.52). All tested methods produced repeatable LS with wCV from 4.4% to 6.5%. The median measurable liver area was smaller for FB-MRE (32%-45%) than that for BH-MRE (91%-93%) (P < 0.05). DATA CONCLUSION: FB-MRE with 60% SG can quantify LS with close agreement and comparable repeatability with respect to BH-MRE in children. LEVEL OF EVIDENCE: 2 TECHNICAL EFFICACY: Stage 1.","journal":"Journal of Magnetic Resonance Imaging","year":2024,"id":461184,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9637,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":388328,"name":"Bradley D. Bolster","orcid":"0000-0003-1474-0969","position":1,"is_corresponding":false},{"id":736001,"name":"Shu‐Fu Shih","orcid":"0000-0002-3812-9091","position":2,"is_corresponding":false},{"id":1061808,"name":"Timoteo Delgado","orcid":"0000-0001-6709-410X","position":3,"is_corresponding":false},{"id":693438,"name":"Vibhas Deshpande","orcid":"0000-0003-0264-6553","position":4,"is_corresponding":false},{"id":341524,"name":"Xiaodong Zhong","orcid":"0000-0001-8355-5279","position":5,"is_corresponding":false},{"id":786936,"name":"Timothy Adamos","orcid":"0000-0002-9234-039X","position":6,"is_corresponding":false},{"id":704846,"name":"Shahnaz Ghahremani","orcid":"0000-0002-4524-2391","position":7,"is_corresponding":false},{"id":354287,"name":"Kara L. Calkins","orcid":"0000-0001-6658-7981","position":8,"is_corresponding":false},{"id":449705,"name":"Holden H. Wu","orcid":"0000-0002-2585-5916","position":9,"is_corresponding":false},{"id":810523,"name":"Sevgi Gökçe Kafalı","orcid":"0000-0001-5941-5399","position":0,"is_corresponding":true}],"reference_count":40,"raw_metadata":null,"created_at":"2026-07-19T02:04:12.271488Z","pmid":"39036994","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}