{"doi":"10.1002/jlcr.1133","title":"Synthesis of <sup>99m</sup>Tc‐labeled organo‐germanium nanoparticles and their <i>in vivo</i> study as a spleen imaging agent","abstract":"<jats:title>Abstract</jats:title><jats:p><jats:sup>99m</jats:sup>Tc‐Labeled organo‐germanium nanoparticles ranging in size from 60 to 80 nm were newly developed for a spleen imaging agent. The radiolabeled nanoparticles were prepared with a high labeling efficiency (over 99%) and they also showed an excellent stability at room temperature for 6 h. The biodistribution data of the nanoparticles injected into rats via intravenous routes showed a notably higher accumulation in the spleen when compared to other reticuloendothelial system organs. Gamma image of the rabbits obtained after an intravenous injection of the nanoparticles revealed a localization of the radioactivity mainly in the spleen and the liver. Copyright © 2006 John Wiley &amp; Sons, Ltd.</jats:p>","journal":"Journal of Labelled Compounds and Radiopharmaceuticals","year":2006,"id":653504,"datarank":0.32958368660043297,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.0,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1705154,"name":"Hui Jeong Gwon","orcid":null,"position":1,"is_corresponding":false},{"id":1705155,"name":"Junhwa Shin","orcid":null,"position":2,"is_corresponding":false},{"id":1463438,"name":"Sang Hyun Park","orcid":"0000-0003-0612-2562","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Synthesis of <sup>99m</sup>Tc‐labeled organo‐germanium nanoparticles and their <i>in vivo</i> study as a spleen imaging agent","abstract":"<jats:title>Abstract</jats:title><jats:p><jats:sup>99m</jats:sup>Tc‐Labeled organo‐germanium nanoparticles ranging in size from 60 to 80 nm were newly developed for a spleen imaging agent. 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