{"doi":"10.1002/jcp.30824","title":"Selenium metabolism and regulation of immune cells in immune‐associated diseases","abstract":"<jats:title>Abstract</jats:title><jats:p>Selenium, as one of the essential microelements, plays an irreplaceable role in metabolism regulation and cell survival. Selenium metabolism and regulation have great effects on physiological systems especially the immune system. Therefore, selenium is tightly related to various diseases like cancer. Although recent research works have revealed much about selenium metabolism, the ways in which selenium regulates immune cells' functions and immune‐associated diseases still remain much unclear. In this review, we will briefly introduce the regulatory role of selenium metabolism in immune cells and immune‐associated diseases.</jats:p>","journal":"Journal of Cellular Physiology","year":2022,"id":625771,"datarank":0.5333022092234121,"base_score":3.5553480614894135,"endowment":3.5553480614894135,"self_citation_contribution":0.5333022092234121,"citation_network_contribution":0.0,"self_endowment_contribution":0.5333022092234121,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":34,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1618532,"name":"Qiuli Yang","orcid":null,"position":1,"is_corresponding":false},{"id":1618533,"name":"Yingjie Dong","orcid":null,"position":2,"is_corresponding":false},{"id":1618534,"name":"Yueru Hou","orcid":null,"position":3,"is_corresponding":false},{"id":1618535,"name":"Guangwei Liu","orcid":"0000-0002-6008-2891","position":4,"is_corresponding":false},{"id":1618531,"name":"Ruiying Niu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Selenium metabolism and regulation of immune cells in immune‐associated diseases","abstract":"<jats:title>Abstract</jats:title><jats:p>Selenium, as one of the essential microelements, plays an irreplaceable role in metabolism regulation and cell survival. Selenium metabolism and regulation have great effects on physiological systems especially the immune system. Therefore, selenium is tightly related to various diseases like cancer. Although recent research works have revealed much about selenium metabolism, the ways in which selenium regulates immune cells' functions and immune‐associated diseases still remain much unclear. In this review, we will briefly introduce the regulatory role of selenium metabolism in immune cells and immune‐associated diseases.</jats:p>","is_dataset_classified":null,"base_score":3.5553480614894135,"endowment":3.5553480614894135,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"35788930","pmcid":null,"openalex_id":"https://openalex.org/W4283814439","authors":[],"funders":[{"funder_name":"National Natural Science Foundation for Key Programs of China","grant_id":"31730024","title":null},{"funder_name":"National Natural Science Foundation for General Programs of China","grant_id":"32170911","title":null},{"funder_name":"Beijing Municipal Natural Science Foundation of China","grant_id":"5202013","title":null}],"total_grants":3,"fwci":3.2088,"citation_percentile":0.92981844,"influential_citations":0,"citation_trend":[{"year":2023,"count":5},{"year":2024,"count":8},{"year":2025,"count":17},{"year":2026,"count":4}],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.30824","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/jcp.30824","host_type":"publisher"},{"url":"https://doi.org/10.1002/jcp.30824","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/35788930","host_type":"repository"}],"fields_of_study":["Selenium in Biological Systems","Trace Elements in Health","Medical and Biological Ozone Research","Humans","Immune System","Immune System Diseases","Neoplasms","Selenium"],"mesh_terms":["Humans","Immune System","Immune System Diseases","Neoplasms","Selenium"],"keywords":["Immune system","Selenium","Metabolism","Cellular metabolism","Biology","Cell metabolism","Immunology","Cell biology","Chemistry","Biochemistry","Infection","Cancer","Immune cells","Inflammation","Selenium Metabolism","Immune-associated Diseases"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.26570083.v1","title":"Additional file 1 of Turning gray selenium and sublimed sulfur into a nanocomposite to accelerate tissue regeneration by isothermal recrystallization","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26570083","title":"Additional file 1 of Turning gray selenium and sublimed sulfur into a nanocomposite to accelerate tissue regeneration by isothermal recrystallization","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-04T07:53:48.076342Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}