{"doi":"10.1002/hed.70129","title":"Health‐Related Quality of Life in Patients Undergoing Surgery for Primary Hyperparathyroidism: Patient Reported Outcome Measures","abstract":"BACKGROUND: Parathyroidectomy is typically curative for primary hyperparathyroidism (PHPT) and may lead to health-related quality of life (HRQL) improvements. We aim to evaluate general and disease-specific HRQL changes in patients undergoing surgery for PHPT from their perspective. METHODS: Patients completed three patient-reported outcome measure (PROM) surveys before and after surgery: (1) Worry survey; (2) Voice Handicap Index-10 (VHI-10); and (3) Patient-Reported Outcome Measurement Information System Global-10 (PROMIS). RESULTS: Forty-four patients were included with a median age of 65 years, with 39 females (89%) included. Thirty-two patients (73%) had a single adenoma, and 12 (27%) had multigland disease (parathyroid hyperplasia). Worry scores related to parathyroid cancer, parathyroid surgery, and parathyroid-related problems significantly improved post-operatively (p < 0.05). On PROMIS assessment, there were improved scores in the physical health domain, mental health domain, and general health following parathyroid surgery for PHPT (p < 0.05). CONCLUSION: Patients with PHPT demonstrated significant improvements in HRQL following surgery.","journal":"Head & Neck","year":2025,"id":585216,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9529,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1499023,"name":"Okenwa C. Okose","orcid":null,"position":1,"is_corresponding":false},{"id":697032,"name":"Amr H. Abdelhamid Ahmed","orcid":"0000-0001-5611-5833","position":2,"is_corresponding":false},{"id":1498587,"name":"Yoshiyuki Saito","orcid":"0000-0002-2462-6775","position":3,"is_corresponding":false},{"id":770448,"name":"Marika D. Russell","orcid":"0000-0001-5436-3649","position":4,"is_corresponding":false},{"id":328709,"name":"Tejas S. Athni","orcid":"0000-0002-6336-0826","position":5,"is_corresponding":false},{"id":1498588,"name":"Amanda Silver Karcioglu","orcid":"0000-0002-1358-774X","position":6,"is_corresponding":false},{"id":1498589,"name":"Anthony Y. Cheung","orcid":"0000-0002-7329-8560","position":7,"is_corresponding":false},{"id":737030,"name":"Adithya Srikanthan","orcid":"0000-0002-0394-7860","position":8,"is_corresponding":false},{"id":1499024,"name":"Christina Alcaro","orcid":null,"position":9,"is_corresponding":false},{"id":1499025,"name":"Anthea Sistovaris","orcid":null,"position":10,"is_corresponding":false},{"id":1499026,"name":"Ian J. Behr","orcid":null,"position":11,"is_corresponding":false},{"id":1498590,"name":"Justin M. Soffer","orcid":"0000-0001-6423-1770","position":12,"is_corresponding":false},{"id":1498591,"name":"Bo Wang","orcid":"0000-0003-1029-3954","position":13,"is_corresponding":false},{"id":1498592,"name":"Tak‐sum Wong","orcid":"0000-0002-5941-8757","position":14,"is_corresponding":false},{"id":1402320,"name":"Defne Altan","orcid":null,"position":15,"is_corresponding":false},{"id":1498593,"name":"Farhad Salem","orcid":"0000-0002-2952-3062","position":16,"is_corresponding":false},{"id":1499027,"name":"Elias Zavaro","orcid":null,"position":17,"is_corresponding":false},{"id":1498594,"name":"Prachya Maneeprasopchoke","orcid":"0000-0001-7099-1776","position":18,"is_corresponding":false},{"id":1498595,"name":"Katherine Larrabee","orcid":"0000-0003-0155-1667","position":19,"is_corresponding":false},{"id":1498596,"name":"Dipti Kamani","orcid":"0000-0003-2765-5413","position":20,"is_corresponding":false},{"id":955228,"name":"Martin Almquist","orcid":"0000-0002-0953-1188","position":21,"is_corresponding":false},{"id":352995,"name":"Frédéric Triponez","orcid":"0000-0001-7808-496X","position":22,"is_corresponding":false},{"id":1078802,"name":"Jennifer J. Shin","orcid":"0000-0002-9741-8491","position":23,"is_corresponding":false},{"id":426662,"name":"Gregory W. Randolph","orcid":"0000-0001-5373-9181","position":24,"is_corresponding":false},{"id":1498586,"name":"Lily N. Trinh","orcid":"0000-0001-8534-6630","position":0,"is_corresponding":true}],"reference_count":22,"raw_metadata":null,"created_at":"2026-07-19T02:59:20.067334Z","pmid":"41392488","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}