{"doi":"10.1002/hed.26308","title":"Outcomes after radiation therapy for<scp>T2N0</scp>/stage<scp>II</scp>glottic squamous cell carcinoma","abstract":"BACKGROUND: We report outcomes for patients with T2N0M0 glottic squamous cell carcinoma (SCC) treated with radiation therapy (RT). METHODS: Patients who received definitive RT for T2 glottic SCC from 2000 through 2013 were retrospectively reviewed. RESULTS: One hundred and thirteen patients were analyzed (median follow-up time 91 months; 85 patients received three-dimensional conformal radiotherapy [3D-CRT] and 28 received intensity-modulated radiation therapy [IMRT]). Fractionation was conventional (58%) or altered (42%); 20 patients (18%) received concurrent chemotherapy. Five-year local control was 83% for the 3D-CRT vs 81% for the IMRT group (P = .76). The ultimate locoregional control at 5 years was 100% for IMRT vs 91% for 3D-CRT (P = .1). The 5-year overall survival (OS) was 78% for 3D-CRT vs 81% for IMRT (P = .83). On multivariate analysis, younger age was the only independent predictor of improved OS (P = .0002). CONCLUSIONS: Oncologic and survival outcomes were excellent for patients with T2N0 glottic cancer. Patients treated with IMRT and 3D-CRT had no statistically significant differences in all investigated endpoints.","journal":"Head & Neck","year":2020,"id":81965,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8178,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":425045,"name":"Bassem Youssef","orcid":null,"position":1,"is_corresponding":false},{"id":351182,"name":"Abdallah Mohamed","orcid":"0000-0003-2064-7613","position":2,"is_corresponding":false},{"id":423556,"name":"Lara Hilal","orcid":"0000-0002-4508-2391","position":3,"is_corresponding":false},{"id":423557,"name":"Blaine D. Smith","orcid":"0000-0002-2636-190X","position":4,"is_corresponding":false},{"id":423558,"name":"Ibrahim Abu‐Gheida","orcid":"0000-0002-3574-4371","position":5,"is_corresponding":false},{"id":425046,"name":"Georges Farha","orcid":null,"position":6,"is_corresponding":false},{"id":351189,"name":"G. Brandon Gunn","orcid":"0000-0001-8197-0380","position":7,"is_corresponding":false},{"id":351187,"name":"Jack Phan","orcid":"0000-0001-5977-6004","position":8,"is_corresponding":false},{"id":423559,"name":"Jan S. Lewin","orcid":"0000-0002-6743-9064","position":9,"is_corresponding":false},{"id":425047,"name":"Apurva Thekdi","orcid":null,"position":10,"is_corresponding":false},{"id":351188,"name":"William H. Morrison","orcid":"0000-0002-9546-0805","position":11,"is_corresponding":false},{"id":299194,"name":"Adam S. Garden","orcid":"0000-0001-7926-2641","position":12,"is_corresponding":false},{"id":295555,"name":"Clifton D. Fuller","orcid":"0000-0002-5264-3994","position":13,"is_corresponding":false},{"id":32353,"name":"David I. Rosenthal","orcid":"0000-0001-7124-7447","position":14,"is_corresponding":false},{"id":423555,"name":"Karine A. Al Feghali","orcid":"0000-0002-5538-1336","position":0,"is_corresponding":true}],"reference_count":53,"raw_metadata":null,"created_at":"2026-07-18T21:53:19.932222Z","pmid":"32484591","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}