{"doi":"10.1002/hed.26151","title":"Neurologic sequelae following radiation with and without chemotherapy for oropharyngeal cancer: Patient reported outcomes study","abstract":"BACKGROUND: There is little data describing neurocognitive late sequelae in patients treated for oropharyngeal cancer. METHODS: Using PROs, scores for \"numbness/tingling\" and \"difficulty remembering\" were assessed. Wilcoxon testing was utilized to compare mean assessment scores (1-10) between treatment subgroups. RESULTS: Four-hundred ninety-seven patients were evaluated and 267 (54%) received chemotherapy. The mean score for numbness/tingling for patients receiving radiation alone was 0.99 and for each chemotherapy subgroup were: Induction chemotherapy (IC), 1.35 (n = 99); concurrent chemotherapy (CCRT), 1.04 (n = 111) and IC + CCRT, 2.48 (n = 57); 30% of patients who received IC + CCRT had scores ≥5. The mean scores for difficulty remembering were XRT: 1.44, chemotherapy: 1.45, and IC + CCRT subgroup: 2.42. CONCLUSIONS: The symptom burden related to peripheral neuropathy and cognitive complaints was minimal. A minority of patients reported high burdens. Particularly, 30% of patients receiving IC + CCRT described moderate to severe numbness/tingling.","journal":"Head & Neck","year":2020,"id":108542,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8272,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":372232,"name":"Mona Kamal","orcid":"0000-0003-1626-2657","position":1,"is_corresponding":false},{"id":351182,"name":"Abdallah Mohamed","orcid":"0000-0003-2064-7613","position":2,"is_corresponding":false},{"id":348525,"name":"Steven J. Frank","orcid":"0000-0001-6517-7884","position":3,"is_corresponding":false},{"id":423559,"name":"Jan S. Lewin","orcid":"0000-0002-6743-9064","position":4,"is_corresponding":false},{"id":351185,"name":"Stephen Y. Lai","orcid":"0000-0001-8301-7286","position":5,"is_corresponding":false},{"id":351188,"name":"William H. Morrison","orcid":"0000-0002-9546-0805","position":6,"is_corresponding":false},{"id":351187,"name":"Jack Phan","orcid":"0000-0001-5977-6004","position":7,"is_corresponding":false},{"id":244404,"name":"Renata Ferrarotto","orcid":"0000-0002-3561-215X","position":8,"is_corresponding":false},{"id":32353,"name":"David I. Rosenthal","orcid":"0000-0001-7124-7447","position":9,"is_corresponding":false},{"id":447333,"name":"Katherine A. Hutcheson","orcid":"0000-0003-3710-5706","position":10,"is_corresponding":false},{"id":295555,"name":"Clifton D. Fuller","orcid":"0000-0002-5264-3994","position":11,"is_corresponding":false},{"id":518284,"name":"Gary B. Gunn","orcid":null,"position":12,"is_corresponding":false},{"id":299194,"name":"Adam S. Garden","orcid":"0000-0001-7926-2641","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-18T23:12:43.081337Z","pmid":"32212359","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}