{"doi":"10.1002/ejic.202300782","title":"Mechanistic Insights into Ru‐catalyzed Alkene Epoxidation with Nitrous Oxide as a Terminal Oxidant","abstract":"Abstract Nitrous oxide (N 2 O) is a greenhouse gas produced in the manufacture of 6,6‐nylon and nitric acid. While an attractive oxidant that releases only N 2 as a by‐product, the kinetic stability of N 2 O typically requires high temperatures and pressures for activation. This work describes initial kinetics of oxygen transfer in the epoxidation of cholesteryl acetate with N 2 O catalysed by D 4 ‐Ru(VI)(por)(O) 2 complexes in efforts to provide a better mechanistic understanding of this chemistry. Insights include a need for low concentrations of the alkene to avoid competitive binding to the metal, possible saturation behavior at high N 2 O pressures, transfer of only one oxygen of Ru VI (O) 2 to substrate and a possible catalyst turnover involving disproportionation of Ru IV (O) and Ru IV (O)(N 2 O) to active Ru VI (O) 2 , Ru IV (O) and N 2 . These insights will be used in future designs of improved catalysts and reaction protocols that may operate efficiently at low pressures of N 2 O and ambident temperature.","journal":"European Journal of Inorganic Chemistry","year":2024,"id":451297,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9536,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1272771,"name":"Ronald Grigg","orcid":null,"position":1,"is_corresponding":false},{"id":295844,"name":"Jennifer M. Schomaker","orcid":"0000-0003-1329-950X","position":2,"is_corresponding":false},{"id":1272289,"name":"Vitaliy I. Timokhin","orcid":"0000-0002-6978-1242","position":0,"is_corresponding":true}],"reference_count":54,"raw_metadata":null,"created_at":"2026-07-19T02:02:41.417944Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}