{"doi":"10.1002/ejhf.2762","title":"Bridging Strategies and Cardiac Replacement Outcomes in Patients with Acute Decompensated Heart Failure-Related Cardiogenic Shock","abstract":"AIMS: To describe outcomes associated with bridging strategies in patients with acute decompensated heart failure-related cardiogenic shock (ADHF-CS) bridged to durable left ventricular assist device (LVAD) or heart transplantation (HTx). METHODS AND RESULTS: Durable LVAD or HTx recipients from 2014 to 2019 with pre-operative ADHF-CS were identified in the Society of Thoracic Surgeons Adult Cardiac Surgery Database and stratified by bridging strategy. The primary outcome was operative or 30-day post-operative mortality. Secondary outcomes included post-operative major bleeding. Exploratory comparisons between bridging strategies and outcomes were performed using overlap weighting with and without covariate adjustment. Among 9783 patients with pre-operative CS, 8777 (89.7%) had ADHF-CS. Medical therapy (n = 5013) was the most common bridging strategy, followed by intra-aortic balloon pump (IABP; n = 2816), catheter-based temporary mechanical circulatory support (TMCS; n = 417), and veno-arterial extracorporeal membrane oxygenation (VA-ECMO; n = 465). Mortality was highest in patients bridged with VA-ECMO (22%), followed by catheter-based TMCS (10%), IABP (9%), and medical therapy (7%). Adverse post-operative outcomes were more frequent in LVAD recipients compared with HTx recipients. CONCLUSION: Among patients with ADHF-CS bridged to HTx or durable LVAD, the highest rates of death and adverse events during index hospitalization were observed in those bridged with VA-ECMO, followed by catheter-based TMCS, IABP, and medical therapy. Patients who received durable LVAD had higher rates of post-operative complications compared with HTx recipients. Prospective trials are needed to define optimal bridging strategies in patients with ADHF-CS.","journal":"European Journal of Heart Failure","year":2023,"id":358059,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7506,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":420371,"name":"David D. Berg","orcid":"0000-0002-0366-5492","position":1,"is_corresponding":false},{"id":557822,"name":"Guohai Zhou","orcid":"0000-0002-8826-403X","position":2,"is_corresponding":false},{"id":536313,"name":"Lauren Sinnenberg","orcid":"0000-0003-2443-2927","position":3,"is_corresponding":false},{"id":445142,"name":"Sameer Hirji","orcid":"0000-0002-5032-675X","position":4,"is_corresponding":false},{"id":260663,"name":"Ersilia M. DeFilippis","orcid":"0000-0002-0493-1326","position":5,"is_corresponding":false},{"id":380428,"name":"Hari R. Mallidi","orcid":"0000-0001-7654-810X","position":6,"is_corresponding":false},{"id":264819,"name":"David A. Morrow","orcid":"0000-0002-9589-5382","position":7,"is_corresponding":false},{"id":380425,"name":"Daniel Rinewalt","orcid":"0000-0001-8304-5412","position":8,"is_corresponding":false},{"id":875108,"name":"Michael M. Givertz","orcid":"0000-0003-1012-7710","position":9,"is_corresponding":false},{"id":231419,"name":"Anubodh S. Varshney","orcid":"0000-0002-9697-8948","position":0,"is_corresponding":true}],"reference_count":22,"raw_metadata":null,"created_at":"2026-07-19T01:13:43.629667Z","pmid":"36597721","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}