{"doi":"10.1002/dvg.22840","title":"Genomic organization of <scp>H</scp>ox and <scp>P</scp>ara<scp>H</scp>ox clusters in the echinoderm, <scp><i>A</i></scp><i>canthaster planci</i>","abstract":"<jats:title>Summary</jats:title><jats:p>The organization of echinoderm Hox clusters is of interest due to the role that Hox genes play in deuterostome development and body plan organization, and the unique gene order of the Hox complex in the sea urchin <jats:italic>Strongylocentrotus purpuratus</jats:italic>, which has been linked to the unique development of the axial region. Here, it has been reported that the Hox and ParaHox clusters of <jats:italic>Acanthaster planci</jats:italic>, a corallivorous starfish found in the Pacific and Indian oceans, generally resembles the chordate and hemichordate clusters. The <jats:italic>A. planci</jats:italic> Hox cluster shared with sea urchins the loss of one of the medial Hox genes, <jats:italic>even‐skipped</jats:italic> (<jats:italic>Evx)</jats:italic> at the anterior of the cluster, as well as organization of the posterior Hox genes. genesis 52:952–958, 2014. © 2014 Wiley Periodicals, Inc.</jats:p>","journal":"genesis","year":2014,"id":609719,"datarank":0.5983476069846413,"base_score":3.9889840465642745,"endowment":3.9889840465642745,"self_citation_contribution":0.5983476069846413,"citation_network_contribution":0.0,"self_endowment_contribution":0.5983476069846413,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":53,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1567268,"name":"Carmel McDougall","orcid":null,"position":1,"is_corresponding":false},{"id":833182,"name":"Scott F. Cummins","orcid":"0000-0002-1454-2076","position":2,"is_corresponding":false},{"id":1567269,"name":"Mike Hall","orcid":null,"position":3,"is_corresponding":false},{"id":837161,"name":"Bernard M. Degnan","orcid":"0000-0001-7573-8518","position":4,"is_corresponding":false},{"id":1517529,"name":"Nori Satoh","orcid":null,"position":5,"is_corresponding":false},{"id":607832,"name":"Eiichi Shoguchi","orcid":"0000-0003-3136-5558","position":6,"is_corresponding":false},{"id":608303,"name":"Kenneth W. Baughman","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Genomic organization of <scp>H</scp>ox and <scp>P</scp>ara<scp>H</scp>ox clusters in the echinoderm, <scp><i>A</i></scp><i>canthaster planci</i>","abstract":"<jats:title>Summary</jats:title><jats:p>The organization of echinoderm Hox clusters is of interest due to the role that Hox genes play in deuterostome development and body plan organization, and the unique gene order of the Hox complex in the sea urchin <jats:italic>Strongylocentrotus purpuratus</jats:italic>, which has been linked to the unique development of the axial region. Here, it has been reported that the Hox and ParaHox clusters of <jats:italic>Acanthaster planci</jats:italic>, a corallivorous starfish found in the Pacific and Indian oceans, generally resembles the chordate and hemichordate clusters. The <jats:italic>A. planci</jats:italic> Hox cluster shared with sea urchins the loss of one of the medial Hox genes, <jats:italic>even‐skipped</jats:italic> (<jats:italic>Evx)</jats:italic> at the anterior of the cluster, as well as organization of the posterior Hox genes. genesis 52:952–958, 2014. © 2014 Wiley Periodicals, Inc.</jats:p>","is_dataset_classified":null,"base_score":3.9889840465642745,"endowment":3.9889840465642745,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"25394327","pmcid":null,"openalex_id":"https://openalex.org/W1935552863","authors":[],"funders":[],"total_grants":0,"fwci":8.2637,"citation_percentile":0.97118332,"influential_citations":0,"citation_trend":[{"year":2015,"count":5},{"year":2016,"count":5},{"year":2017,"count":4},{"year":2018,"count":7},{"year":2020,"count":2},{"year":2021,"count":6},{"year":2022,"count":13},{"year":2023,"count":6},{"year":2024,"count":3},{"year":2025,"count":2}],"oa_status":"bronze","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvg.22840","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvg.22840","host_type":"publisher"},{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fdvg.22840","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvg.22840","host_type":"publisher"},{"url":"https://doi.org/10.1002/dvg.22840","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/25394327","host_type":"repository"},{"url":"http://hdl.handle.net/10072/343151","host_type":""}],"fields_of_study":["Echinoderm biology and ecology","Marine and coastal plant biology","Marine Biology and Environmental Chemistry"],"mesh_terms":["Animals","Genes, Homeobox","Multigene Family","Phylogeny","Sea Urchins","Starfish","Gene Deletion","Evolution, Molecular"],"keywords":["Chordate","Hox gene","Acanthaster","Echinoderm","Starfish","Body plan","Sea urchin","Biology","Deuterostome","Strongylocentrotus purpuratus","Evolutionary biology","Anatomy","Cell biology","Gene","Vertebrate","Genetics","Ecology","Reef","Gene expression","Hox cluster","Acanthaster Planci","Parahox Cluster","Echinoderm Development","Starfish Genome"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-31T13:51:10.203399Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}