{"doi":"10.1002/dad2.70043","title":"Feasibility, validity, and normative data for the remote Uniform Data Set neuropsychological battery at the University of Pennsylvania Alzheimer's Disease Research Center","abstract":"INTRODUCTION: We investigated the feasibility and validity of the remotely-administered neuropsychological battery from the National Alzheimer's Coordinating Center Uniform Data Set (UDS T-Cog). METHODS: Two hundred twenty Penn Alzheimer's Disease Research Center participants with unimpaired cognition, mild cognitive impairment, and dementia completed the T-Cog during their annual UDS evaluation. We assessed administration feasibility and diagnostic group differences cross-sectionally across telephone versus videoconference modalities, and compared T-Cog to prior in-person UDS scores longitudinally. RESULTS: Administration time averaged 54 min and 79% of participants who initiated a T-Cog completed all 12 subtests; completion time and rates differed by diagnostic group but not by modality. Performance varied expectedly across groups with moderate to strong associations between most T-Cog measures and in-person correlates, although select subtests demonstrated lower comparability. DISCUSSION: The T-Cog is feasibly administered and shows preliminary validity in a cognitively heterogeneous cohort. Normative data from this cohort should be expanded to more diverse populations to enhance utility and generalizability. Highlights: This study examined the feasibility and validity of the remote Uniform Data Set (also known as the T-Cog) and contributes key normative data for widespread use.A remote neuropsychological battery was feasibly administered with high overall engagement and completion rates, adequate reliability compared to in-person testing, and evidence of validity across diagnostic groups.Typical barriers to administration included hearing impairment, technology issues, and distractions; hearing difficulties were particularly common among cognitively impaired groups.Certain tests were less closely related to their in-person correlates and should be used with caution.","journal":"Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring","year":2024,"id":482776,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":22.178386323199504,"corpus_rank":9377,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.9072,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1323278,"name":"Yidan Shi","orcid":"0000-0002-3190-6724","position":1,"is_corresponding":false},{"id":1323699,"name":"Laura Schankel","orcid":null,"position":2,"is_corresponding":false},{"id":1323279,"name":"Naila Albertina de Oliveira","orcid":"0000-0001-8340-5334","position":3,"is_corresponding":false},{"id":481662,"name":"Melissa Kelley","orcid":"0000-0002-0563-0429","position":4,"is_corresponding":false},{"id":66635,"name":"Hannah McCoubrey","orcid":null,"position":5,"is_corresponding":false},{"id":1323700,"name":"Sara Manning Peskin","orcid":null,"position":6,"is_corresponding":false},{"id":1101348,"name":"Kyra O’Brien","orcid":"0000-0002-8461-0492","position":7,"is_corresponding":false},{"id":227428,"name":"Sharon X. Xie","orcid":"0000-0002-7886-4103","position":8,"is_corresponding":false},{"id":230045,"name":"David A. Wolk","orcid":"0000-0002-3554-3481","position":9,"is_corresponding":false},{"id":899557,"name":"Dawn Mechanic‐Hamilton","orcid":"0000-0002-8728-2420","position":10,"is_corresponding":false},{"id":817277,"name":"Katherine Hackett","orcid":"0000-0002-3595-1418","position":0,"is_corresponding":true}],"reference_count":48,"raw_metadata":null,"created_at":"2026-07-19T02:07:18.280369Z","pmid":"39726731","pmcid":"PMC11670303","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}