{"doi":"10.1002/dad2.12484","title":"Neighborhood greenspace and neighborhood income associated with white matter grade worsening: Cardiovascular Health Study","abstract":"INTRODUCTION: We examined whether a combined measure of neighborhood greenspace and neighborhood median income was associated with white matter hyperintensity (WMH) and ventricle size changes. METHODS: The sample included 1260 cognitively normal ≥ 65-year-olds with two magnetic resonance images (MRI; ≈ 5 years apart). WMH and ventricular size were graded from 0 (least) to 9 (most) abnormal (worsening = increase of ≥1 grade from initial to follow-up MRI scans). The four-category neighborhood greenspace-income measure was based on median neighborhood greenspace and income values at initial MRI. Multivariable logistic regression tested associations between neighborhood greenspace-income and MRI measures (worsening vs. not). RESULTS: White matter grade worsening was more likely for those in lower greenspace-lower income neighborhoods than higher greenspace-higher income neighborhoods (odds ratio = 1.73; 95% confidence interval = 1.19-2.51). DISCUSSION: The combination of lower neighborhood income and lower greenspace may be a risk factor for worsening white matter grade on MRI. However, findings need to be replicated in more diverse cohorts. HIGHLIGHTS: Population-based cohort of older adults (≥ 65 years) with greenspace and MRI dataCombined measure of neighborhood greenspace and neighborhood income at initial MRIMRI outcomes included white matter hyperintensities (WMH) and ventricular sizeLongitudinal change in MRI outcomes measured approximately 5 years apartWorsening WMH over time more likely for lower greenspace-lower income neighborhoods.","journal":"Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring","year":2023,"id":358777,"datarank":0.5120732206771923,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.13933722320899214,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.13933722320899214,"corpus_percentile":62.365591397849464,"corpus_rank":4866,"citation_count":11,"citer_count":7,"citers_with_citation_signal":4,"citers_with_endowment":4,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.536,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":430753,"name":"Gina S. Lovasi","orcid":"0000-0003-2613-9599","position":1,"is_corresponding":false},{"id":1109140,"name":"Joyce Jiménez Zambrano","orcid":"0000-0002-1142-8243","position":2,"is_corresponding":false},{"id":1109527,"name":"Simone Camacho","orcid":null,"position":3,"is_corresponding":false},{"id":1109528,"name":"Devi Dhanekula","orcid":null,"position":4,"is_corresponding":false},{"id":541078,"name":"Yvonne L. Michael","orcid":"0000-0002-1494-8498","position":5,"is_corresponding":false},{"id":443421,"name":"Parveen K. Garg","orcid":"0000-0002-6482-2711","position":6,"is_corresponding":false},{"id":430752,"name":"Jana A. Hirsch","orcid":"0000-0003-3355-5558","position":7,"is_corresponding":false},{"id":267326,"name":"David S. Siscovick","orcid":"0000-0003-0461-175X","position":8,"is_corresponding":false},{"id":437810,"name":"Philip M. Hurvitz","orcid":"0000-0002-2944-0785","position":9,"is_corresponding":false},{"id":276461,"name":"Mary L. Biggs","orcid":null,"position":10,"is_corresponding":false},{"id":108598,"name":"James E. Galvin","orcid":"0000-0001-5678-245X","position":11,"is_corresponding":false},{"id":108718,"name":"Traci M. Bartz","orcid":"0000-0003-3403-8763","position":12,"is_corresponding":false},{"id":17627,"name":"W.T. Longstreth","orcid":null,"position":13,"is_corresponding":false},{"id":439560,"name":"Lilah M. Besser","orcid":"0000-0001-9945-0877","position":0,"is_corresponding":true}],"reference_count":58,"raw_metadata":null,"created_at":"2026-07-19T01:13:48.379546Z","pmid":"37885920","pmcid":"PMC10598801","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}