{"doi":"10.1002/dad2.12400","title":"Sensory impairment and algorithmic classification of early cognitive impairment","abstract":"INTRODUCTION: Sensory impairment (SI) is linked to cognitive decline, but its association with early cognitive impairment (ECI) is unclear. METHODS: Sensory functions (vision, hearing, vestibular function, proprioception, and olfaction) were measured between 2012 and 2018 in 414 Baltimore Longitudinal Study of Aging (BLSA) participants (age 74 ± 9 years; 55% women). ECI was defined as 1 standard deviation below age-, sex-, race-, and education-specific mean performance in Card Rotations or California Verbal Learning Test immediate recall. Log binomial models (cross-sectional analysis) and Cox regression models (time-to-event analysis) were used to examine the association between SI and ECI. RESULTS: = 0.02). Longitudinally, there was no significant association between SI and incident ECI over up to 6 years of follow-up. DISCUSSION: SI is associated with higher prevalence, but not incident ECI. Future studies with large sample sizes need to further elucidate the relationship between SI and ECI. Highlights: Sensory impairment is associated with high prevalence of early cognitive impairmentMultisensory impairment may pose a strong risk of early changes in cognitive functionIdentifying multisensory impairment may help early detection of dementia.","journal":"Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring","year":2023,"id":359270,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7806,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":264188,"name":"Jennifer A. Schrack","orcid":"0000-0001-9244-9267","position":1,"is_corresponding":false},{"id":322305,"name":"Alden L. Gross","orcid":"0000-0002-4678-0562","position":2,"is_corresponding":false},{"id":284975,"name":"Nicole M. Armstrong","orcid":"0000-0002-2479-1076","position":3,"is_corresponding":false},{"id":291486,"name":"Bonnielin K. Swenor","orcid":"0000-0002-6044-0951","position":4,"is_corresponding":false},{"id":482269,"name":"Jennifer A. Deal","orcid":"0000-0002-6985-048X","position":5,"is_corresponding":false},{"id":633204,"name":"Frank R. Lin","orcid":"0000-0002-6458-1196","position":6,"is_corresponding":false},{"id":712028,"name":"Hang Wang","orcid":"0009-0004-1251-6132","position":7,"is_corresponding":false},{"id":286278,"name":"Qu Tian","orcid":"0000-0003-2706-1439","position":8,"is_corresponding":false},{"id":254759,"name":"Yang An","orcid":"0000-0002-3312-7265","position":9,"is_corresponding":false},{"id":264194,"name":"Eleanor M. Simonsick","orcid":"0000-0002-5460-3494","position":10,"is_corresponding":false},{"id":21956,"name":"Luigi Ferrucci","orcid":"0000-0002-6273-1613","position":11,"is_corresponding":false},{"id":230044,"name":"Susan M. Resnick","orcid":"0000-0003-1115-7145","position":12,"is_corresponding":false},{"id":322316,"name":"Yuri Agrawal","orcid":"0000-0002-5438-1537","position":13,"is_corresponding":false},{"id":321098,"name":"Yurun Cai","orcid":"0000-0001-8264-8158","position":0,"is_corresponding":true}],"reference_count":47,"raw_metadata":null,"created_at":"2026-07-19T01:13:52.889556Z","pmid":"37063388","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}