{"doi":"10.1002/cncr.35844","title":"In vitro fertilization with cryopreserved oocytes or embryos after cancer: The role of gestational carriers","abstract":"BACKGROUND: Fertility preservation counseling is recommended for reproductive-age cancer patients. Gestational carriers are individuals who carry a pregnancy for someone else. This service creates a path to biological children when cancer treatment necessitates the removal of the uterus. The authors examined the involvement of gestational carriers among women diagnosed with cancer. METHODS: Using data from eight statewide cancer registries linked with the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System, the authors identified women with a cancer diagnosis who subsequently initiated in vitro fertilization (IVF) procedures during 2004 to 2018. Modified Poisson models were used to estimate prevalence ratios (PR) and 95% confidence intervals (CI). Discrete Cox regression models were used to calculate hazard ratios (HR) and CI. Multivariable models adjusted for age, state, and calendar year. RESULTS: Among 1095 women with cancer who used IVF with cryopreserved oocytes or embryos to attempt pregnancy, 19.1% worked with a gestational carrier. Involving gestational carriers was more common among those who initiated IVF for fertility preservation versus after cancer treatment (PR, 1.96; 95% CI, 1.54-2.50) and had chemotherapy versus no chemotherapy (PR, 1.92; 95% CI, 1.50-2.47). Using donor oocytes or embryos (vs. autologous) was more common among women who worked with a gestational carrier (PR, 1.62; 95% CI, 1.17-2.24). Working with a gestational carrier was not associated with conception (HR, 1.06; 95% CI, 0.82-1.37). CONCLUSIONS: Approximately one in five women diagnosed with cancer who used IVF to attempt pregnancy worked with a gestational carrier. The results of this study emphasize the need for information on gestational carriers during fertility preservation counseling.","journal":"Cancer","year":2025,"id":539229,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9582,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1135234,"name":"Alexis C. Wardell","orcid":"0000-0003-1413-3464","position":1,"is_corresponding":false},{"id":349846,"name":"Allison M. Deal","orcid":"0000-0003-3526-3938","position":2,"is_corresponding":false},{"id":520798,"name":"Jennifer E. Mersereau","orcid":"0000-0003-2393-0836","position":3,"is_corresponding":false},{"id":1232648,"name":"Katie Cameron","orcid":null,"position":4,"is_corresponding":false},{"id":232344,"name":"Steven D. Spandorfer","orcid":"0000-0003-2539-0597","position":5,"is_corresponding":false},{"id":1426758,"name":"Gaya Murugappan","orcid":null,"position":6,"is_corresponding":false},{"id":247246,"name":"Valerie L. Baker","orcid":"0000-0003-1762-7339","position":7,"is_corresponding":false},{"id":267506,"name":"Carey K. Anders","orcid":"0000-0001-9165-4074","position":8,"is_corresponding":false},{"id":1146052,"name":"Sara Mitra","orcid":"0000-0002-0721-1375","position":9,"is_corresponding":false},{"id":349844,"name":"Chelsea Anderson","orcid":"0000-0001-6535-481X","position":10,"is_corresponding":false},{"id":336207,"name":"Jianwen Cai","orcid":"0000-0002-4945-6733","position":11,"is_corresponding":false},{"id":275138,"name":"Barbara Luke","orcid":"0000-0002-0405-8133","position":12,"is_corresponding":false},{"id":275144,"name":"Hazel B. Nichols","orcid":"0000-0003-0972-1560","position":13,"is_corresponding":false},{"id":863595,"name":"Taylor D. Ellington","orcid":"0000-0002-5938-7719","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-19T02:52:30.048313Z","pmid":"40220267","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}