{"doi":"10.1002/cncr.34359","title":"Mental health disorders are more common in patients with Hodgkin lymphoma and may negatively impact overall survival","abstract":"BACKGROUND: Long-term mental health outcomes were characterized in patients who were diagnosed with Hodgkin lymphoma (HL), and risk factors for the development of mental health disorders were identified. METHODS: Patients who were diagnosed with HL between 1997 and 2014 were identified in the Utah Cancer Registry. Each patient was matched with up to five individuals from a general population cohort identified within the Utah Population Database, a unique source of linked records that includes patient and demographic data. RESULTS: In total, 795 patients who had HL were matched with 3575 individuals from the general population. Compared with the general population, patients who had HL had a higher risk of any mental health diagnosis (hazard ratio, 1.77; 95% confidence interval, 1.57-2.00). Patients with HL had higher risks of anxiety, depression, substance-related disorders, and suicide and intentional self-inflicted injuries compared with the general population. The main risk factor associated with an increased risk of being diagnosed with mental health disorders was undergoing hematopoietic stem cell transplantation, with a hazard ratio of 2.06 (95% confidence interval, 1.53-2.76). The diagnosis of any mental health disorder among patients with HL was associated with a detrimental impact on overall survival; the 10-year overall survival rate was 70% in patients who had a mental health diagnosis compared with 86% in those patients without a mental health diagnosis (p < .0001). CONCLUSIONS: Patients who had HL had an increased risk of various mental health disorders compared with a matched general population. The current data illustrate the importance of attention to mental health in HL survivorship, particularly for patients who undergo therapy with hematopoietic stem cell transplantation.","journal":"Cancer","year":2022,"id":266642,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6167,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":926763,"name":"Yuji Chen","orcid":"0009-0005-3889-0912","position":1,"is_corresponding":false},{"id":777189,"name":"Seungmin Kim","orcid":"0000-0002-9173-4047","position":2,"is_corresponding":false},{"id":777188,"name":"Krista Ocier","orcid":"0000-0002-5822-3552","position":3,"is_corresponding":false},{"id":435677,"name":"Shane Lloyd","orcid":"0000-0002-4235-7652","position":4,"is_corresponding":false},{"id":926764,"name":"Matthew M. Poppe","orcid":"0000-0002-9573-1329","position":5,"is_corresponding":false},{"id":348721,"name":"Catherine J. Lee","orcid":"0000-0003-2587-8955","position":6,"is_corresponding":false},{"id":450428,"name":"Martha Glenn","orcid":null,"position":7,"is_corresponding":false},{"id":402281,"name":"Ken R. Smith","orcid":"0000-0003-0682-3705","position":8,"is_corresponding":false},{"id":777191,"name":"Alison Fraser","orcid":"0000-0003-1681-698X","position":9,"is_corresponding":false},{"id":777190,"name":"Vikrant Deshmukh","orcid":"0000-0001-6670-8245","position":10,"is_corresponding":false},{"id":495271,"name":"Michael Newman","orcid":"0000-0002-3147-6058","position":11,"is_corresponding":false},{"id":739509,"name":"John Snyder","orcid":"0009-0001-1504-145X","position":12,"is_corresponding":false},{"id":569204,"name":"Kerry Rowe","orcid":"0000-0002-0500-9819","position":13,"is_corresponding":false},{"id":258168,"name":"David K. Gaffney","orcid":"0000-0002-5752-1611","position":14,"is_corresponding":false},{"id":889776,"name":"Ben Haaland","orcid":null,"position":15,"is_corresponding":false},{"id":269021,"name":"Mia Hashibe","orcid":null,"position":16,"is_corresponding":false},{"id":679708,"name":"Randa Tao","orcid":"0000-0001-9379-4732","position":0,"is_corresponding":true}],"reference_count":31,"raw_metadata":null,"created_at":"2026-07-19T00:26:58.102271Z","pmid":"35916651","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}