{"doi":"10.1002/cam4.7007","title":"Neighborhood social vulnerability and disparities in time to kidney cancer surgical treatment and survival in Arizona","abstract":"BACKGROUND: Hispanics and American Indians (AI) have high kidney cancer incidence and mortality rates in Arizona. This study assessed: (1) whether racial and ethnic minority patients and patients from neighborhoods with high social vulnerability index (SVI) experience a longer time to surgery after clinical diagnosis, and (2) whether time to surgery, race and ethnicity, and SVI are associated with upstaging to pT3/pT4, disease-free survival (DFS), and overall survival (OS). METHODS: Arizona Cancer Registry (2009-2018) kidney and renal pelvis cases (n = 4592) were analyzed using logistic regression models to assess longer time to surgery and upstaging. Cox-regression hazard models were used to test DFS and OS. RESULTS: Hispanic and AI patients with T1 tumors had a longer time to surgery than non-Hispanic White patients (median time of 56, 55, and 45 days, respectively). Living in neighborhoods with high (≥75) overall SVI increased odds of a longer time to surgery for cT1a (OR 1.54, 95% CI: 1.02-2.31) and cT2 (OR 2.32, 95% CI: 1.13-4.73). Race and ethnicity were not associated with time to surgery. Among cT1a patients, a longer time to surgery increased odds of upstaging to pT3/pT4 (OR 1.95, 95% CI: 0.99-3.84). A longer time to surgery was associated with PFS (HR 1.52, 95% CI: 1.17-1.99) and OS (HR 1.63, 95% CI: 1.26-2.11). Among patients with cT2 tumor, living in high SVI neighborhoods was associated with worse OS (HR 1.66, 95% CI: 1.07-2.57). CONCLUSIONS: High social vulnerability was associated with increased time to surgery and poor survival after surgery.","journal":"Cancer Medicine","year":2024,"id":441963,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9599,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":922265,"name":"Patrick Wightman","orcid":null,"position":1,"is_corresponding":false},{"id":921854,"name":"Kristin E. Morrill","orcid":"0000-0001-9970-4937","position":2,"is_corresponding":false},{"id":361612,"name":"Chiu‐Hsieh Hsu","orcid":"0000-0002-7451-4018","position":3,"is_corresponding":false},{"id":827183,"name":"Hina Arif‐Tiwari","orcid":"0000-0003-0837-0682","position":4,"is_corresponding":false},{"id":581896,"name":"Eric Kauffman","orcid":null,"position":5,"is_corresponding":false},{"id":931677,"name":"Francine C. Gachupin","orcid":"0000-0003-2349-6486","position":6,"is_corresponding":false},{"id":1099324,"name":"Juan Chipollini","orcid":"0000-0003-2603-0382","position":7,"is_corresponding":false},{"id":1117479,"name":"Benjamin R. Lee","orcid":"0000-0001-6558-4551","position":8,"is_corresponding":false},{"id":413903,"name":"David O. Garcia","orcid":"0000-0001-6669-9457","position":9,"is_corresponding":false},{"id":332037,"name":"Ken Batai","orcid":"0000-0002-0317-1118","position":10,"is_corresponding":false},{"id":931676,"name":"Celina I. Valencia","orcid":"0000-0002-1452-867X","position":0,"is_corresponding":true}],"reference_count":56,"raw_metadata":null,"created_at":"2026-07-19T02:01:11.152920Z","pmid":"38400688","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}