{"doi":"10.1002/brb3.70976","title":"The Relationship Between Subacute Pain, Chronic Pain, and Sleep Disorder: A Cross‐Sectional Study Based on NHANES (2009–2010)","abstract":"<jats:title>ABSTRACT</jats:title>\n                  <jats:sec>\n                    <jats:title>Background</jats:title>\n                    <jats:p>Chronic pain (CP) and subacute pain (SAP) represent major public health challenges, frequently coexisting with sleep disorders (SD). However, the association between pain duration and SD remains poorly characterized.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:</jats:title>\n                    <jats:p>This cross‐sectional study analyzed data from the National Health and Nutrition Examination Survey (NHANES, 2009–2010). CP, SAP, and SD were assessed through structured interviews conducted by trained personnel using the Computer‐Assisted Personal Interviewing (CAPI) system. Multivariable logistic regression models were employed to evaluate the relationship between pain duration (CP vs. SAP) and SD, while subgroup analyses explored potential effect modifications by analgesic use and pain intensity.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Results</jats:title>\n                    <jats:p>\n                      Among 1,109 participants, after adjusting for confounders, individuals with CP exhibited an 85% higher likelihood of SD compared to those with SAP (OR = 1.85, 95% CI: 1.39–2.47,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001). Pain that worsened during the day (OR = 1.95, 95% CI: 1.35–2.80,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001), persisted at rest (OR = 2.38, 95% CI: 1.65–3.43,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001), failed to be alleviated by exercise (OR = 1.59, 95% CI: 1.20–2.11,\n                      <jats:italic>p</jats:italic>\n                      = 0.001), and awakened from (OR = 2.70, 95% CI: 2.06–3.55,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001) was significantly associated with SD. Subgroup analyses revealed no significant interaction effects of analgesic use or pain intensity on the CP/SAP‐SD association (\n                      <jats:italic>p</jats:italic>\n                      for interaction &gt; 0.05).\n                    </jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion</jats:title>\n                    <jats:p>These findings suggest that pain (both subacute and chronic) may be an independent risk factor for SD, supporting the need for early intervention for SAP.</jats:p>\n                  </jats:sec>","journal":"Brain and Behavior","year":2025,"id":633884,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1643663,"name":"Gaohui Wu","orcid":null,"position":1,"is_corresponding":false},{"id":236908,"name":"Minxian Wang","orcid":"0000-0002-3753-508X","position":2,"is_corresponding":false},{"id":190442,"name":"Shuai Zhao","orcid":"0000-0001-6215-9453","position":3,"is_corresponding":false},{"id":114289,"name":"Yanlin Yang","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Relationship Between Subacute Pain, Chronic Pain, and Sleep Disorder: A Cross‐Sectional Study Based on NHANES (2009–2010)","abstract":"<jats:title>ABSTRACT</jats:title>\n                  <jats:sec>\n                    <jats:title>Background</jats:title>\n                    <jats:p>Chronic pain (CP) and subacute pain (SAP) represent major public health challenges, frequently coexisting with sleep disorders (SD). However, the association between pain duration and SD remains poorly characterized.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:</jats:title>\n                    <jats:p>This cross‐sectional study analyzed data from the National Health and Nutrition Examination Survey (NHANES, 2009–2010). CP, SAP, and SD were assessed through structured interviews conducted by trained personnel using the Computer‐Assisted Personal Interviewing (CAPI) system. Multivariable logistic regression models were employed to evaluate the relationship between pain duration (CP vs. SAP) and SD, while subgroup analyses explored potential effect modifications by analgesic use and pain intensity.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Results</jats:title>\n                    <jats:p>\n                      Among 1,109 participants, after adjusting for confounders, individuals with CP exhibited an 85% higher likelihood of SD compared to those with SAP (OR = 1.85, 95% CI: 1.39–2.47,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001). Pain that worsened during the day (OR = 1.95, 95% CI: 1.35–2.80,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001), persisted at rest (OR = 2.38, 95% CI: 1.65–3.43,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001), failed to be alleviated by exercise (OR = 1.59, 95% CI: 1.20–2.11,\n                      <jats:italic>p</jats:italic>\n                      = 0.001), and awakened from (OR = 2.70, 95% CI: 2.06–3.55,\n                      <jats:italic>p</jats:italic>\n                      &lt; 0.001) was significantly associated with SD. Subgroup analyses revealed no significant interaction effects of analgesic use or pain intensity on the CP/SAP‐SD association (\n                      <jats:italic>p</jats:italic>\n                      for interaction &gt; 0.05).\n                    </jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion</jats:title>\n                    <jats:p>These findings suggest that pain (both subacute and chronic) may be an independent risk factor for SD, supporting the need for early intervention for SAP.</jats:p>\n                  </jats:sec>","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"41121759","pmcid":"PMC12541131","openalex_id":"https://openalex.org/W4415415315","authors":[],"funders":[{"funder_name":"Fundamental Research Funds for the Central Universities","grant_id":"2042023kf0092","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"82401415","title":null},{"funder_name":"Innovation and Cultivation Fund for Zhongnan Hospital of Wuhan University","grant_id":"CXPY2023031","title":null}],"total_grants":3,"fwci":2.2728,"citation_percentile":0.89177209,"influential_citations":0,"citation_trend":[{"year":2026,"count":2}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.70976","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.70976","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/brb3.70976","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/brb3.70976","host_type":"publisher"},{"url":"https://doi.org/10.1002/brb3.70976","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/41121759","host_type":"repository"},{"url":"https://doaj.org/article/b08ed50e708f413bbaffb140d29823e5","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12541131","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC12541131","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC12541131?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Sleep and related disorders","Musculoskeletal pain and rehabilitation","Fibromyalgia and Chronic Fatigue Syndrome Research","Humans","Cross-Sectional Studies","Male","Female","Chronic Pain","Middle Aged","Adult","Sleep Wake Disorders","Nutrition Surveys","Aged","Acute Pain","United States"],"mesh_terms":["Adult","Aged","Cross-Sectional Studies","Female","Humans","Male","Middle Aged","Nutrition Surveys","Sleep Wake Disorders","United States","Chronic Pain","Acute Pain"],"keywords":["Sleep (system call)","Risk factor","Intervention (counseling)","Young adult","Chronic pain","Sleep disorder","Nhanes","Subacute Pain"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T12:49:16.329188Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}