{"doi":"10.1002/bjs.10488","title":"Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair","abstract":"<jats:title>Abstract</jats:title>\n               <jats:sec>\n                  <jats:title>Background</jats:title>\n                  <jats:p>Pain is the most likely reason for delay in resuming normal activities after groin hernia repair. The primary aim of this study was to determine whether the use of glue to fix the mesh instead of sutures reduced acute postoperative pain after inguinal hernia repair. Secondary objectives were to compare postoperative complications, chronic pain and early recurrence rates during 1-year follow-up.</jats:p>\n               </jats:sec>\n               <jats:sec>\n                  <jats:title>Methods</jats:title>\n                  <jats:p>Some 370 patients who underwent Lichtenstein hernia repair were randomized to receive either glue (Histoacryl®) or non-absorbable polypropylene sutures for fixation of lightweight polypropylene mesh. Postoperative complications, pain and recurrence were evaluated by an independent blinded observer.</jats:p>\n               </jats:sec>\n               <jats:sec>\n                  <jats:title>Results</jats:title>\n                  <jats:p>Postoperative pain at 8 h, 24 h, 7 days and 30 days was less when glue was used instead of sutures for all measures (P &amp;lt; 0·001). The operation was significantly quicker using glue (mean(s.d.) 35·3(8·7) min versus 39·9(11·1) min for sutures; P &amp;lt; 0·001). There were no significant differences between the groups in terms of postoperative complications, chronic pain and early recurrence at 1-year follow-up.</jats:p>\n               </jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion</jats:title>\n                  <jats:p>Atraumatic mesh fixation with glue was quicker and resulted in less acute postoperative pain than sutures for Lichtenstein hernia repair. Registration number: NCT02632097 (http://www.clinicaltrials.gov).</jats:p>\n               </jats:sec>","journal":"British Journal of Surgery","year":2017,"id":20194,"datarank":1.8799162360539194,"base_score":3.6635616461296463,"endowment":3.6635616461296463,"self_citation_contribution":0.5495342469194471,"citation_network_contribution":1.3303819891344724,"self_endowment_contribution":0.5495342469194471,"citer_contribution":1.3303819891344724,"corpus_percentile":null,"corpus_rank":null,"citation_count":38,"citer_count":33,"citers_with_citation_signal":24,"citers_with_endowment":24,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":134320,"name":"M Juvany","orcid":null,"position":1,"is_corresponding":false},{"id":134321,"name":"F Carvajal","orcid":null,"position":2,"is_corresponding":false},{"id":134322,"name":"A Veres","orcid":null,"position":3,"is_corresponding":false},{"id":134323,"name":"D Troyano","orcid":null,"position":4,"is_corresponding":false},{"id":134324,"name":"M Trias","orcid":null,"position":5,"is_corresponding":false},{"id":134325,"name":"A Martrat","orcid":null,"position":6,"is_corresponding":false},{"id":134326,"name":"J Ardid","orcid":null,"position":7,"is_corresponding":false},{"id":134327,"name":"J Obiols","orcid":null,"position":8,"is_corresponding":false},{"id":134328,"name":"M López-Cano","orcid":null,"position":9,"is_corresponding":false},{"id":134319,"name":"C Hoyuela","orcid":"0000-0002-6539-0439","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":3.6635616461296463,"endowment":3.6635616461296463,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28218406","pmcid":null,"openalex_id":"https://openalex.org/W2591138587","authors":[],"funders":[],"total_grants":0,"fwci":3.7404,"citation_percentile":0.93030035,"influential_citations":2,"citation_trend":[{"year":2017,"count":3},{"year":2018,"count":6},{"year":2019,"count":4},{"year":2020,"count":2},{"year":2021,"count":7},{"year":2022,"count":5},{"year":2023,"count":4},{"year":2024,"count":4},{"year":2025,"count":3}],"oa_status":"closed","license":"https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model","oa_locations":[{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbjs.10488","host_type":"publisher"},{"url":"https://academic.oup.com/bjs/article-pdf/104/6/688/46374607/bjs10488.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1002/bjs.10488","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28218406","host_type":"repository"}],"fields_of_study":["Hernia repair and management","Sports injuries and prevention","Surgical Sutures and Adhesives","Medicine","Adult","Aftercare","Aged","Aged, 80 and over","Double-Blind Method","Female","Hernia, Inguinal","Herniorrhaphy","Humans","Male","Middle Aged","Operative Time","Pain Measurement","Postoperative Pain","Postoperative Care","Postoperative Complications","Prospective Studies","Surgical Mesh","Sutures","Tissue Adhesives","Young Adult"],"mesh_terms":["Adult","Aftercare","Aged","Aged, 80 and over","Double-Blind Method","Female","Hernia, Inguinal","Humans","Male","Middle Aged","Pain Measurement","Postoperative Pain","Pain, Postoperative","Postoperative Care","Postoperative Complications","Prospective Studies","Surgical Mesh","Sutures","Tissue Adhesives","Young Adult","Herniorrhaphy","Operative Time"],"keywords":["Medicine","GLUE","Surgery","Hernia repair","Groin","Inguinal hernia","Hernia","Randomized controlled trial","Chronic pain","Fixation (population genetics)","Postoperative pain","Anesthesia"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-04T07:38:57.494152Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}