{"doi":"10.1002/anie.202504419","title":"Synthesis of Chiral δ‐Aminoboronic Esters by Enantioselective Hydrogenation of 1,2‐Azaborines","abstract":"Abstract We describe herein an iridium‐catalyzed highly diastereo‐ and enantioselective hydrogenation of 1,2‐azaborines to access δ‐aminoboronic esters of potential biological importance. This method represents the first enantioselective hydrogenation of a boron‐containing heteroarene and features diverse substitution patterns and wide scope. The synthetic utility of our method was demonstrated by the synthesis of (−)‐phenibut and the formal synthesis of (+)‐3‐PPP and fluvirucinine A 1 .","journal":"Angewandte Chemie International Edition","year":2025,"id":532200,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9427,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1081348,"name":"Yuping Dai","orcid":null,"position":1,"is_corresponding":false},{"id":1413803,"name":"Devon Robinson","orcid":null,"position":2,"is_corresponding":false},{"id":1413396,"name":"Bo Li","orcid":"0000-0002-3726-2640","position":3,"is_corresponding":false},{"id":694789,"name":"Karinne Miqueu","orcid":"0000-0002-5960-1877","position":4,"is_corresponding":false},{"id":694790,"name":"Shih‐Yuan Liu","orcid":"0000-0003-3148-9147","position":5,"is_corresponding":false},{"id":1413802,"name":"Jiangpeng Liu","orcid":null,"position":0,"is_corresponding":true}],"reference_count":82,"raw_metadata":null,"created_at":"2026-07-19T02:51:23.237536Z","pmid":"40192605","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}