{"doi":"10.1002/anie.202305409","title":"Gold‐Catalyzed Amine Cascade Addition to Diyne‐Ene: Enantioselective Synthesis of 1,2‐Dihydropyridines","abstract":"With the well-documented chemical and biological applications, piperidine and pyridine are among the most important N-heterocycles, and a new synthetic strategy, especially one with an alternative bond-forming design, is of general interest. Using the gold-catalyzed intermolecular condensation of amine and diyne-ene, we report herein the first example of enantioselective 1,2-dihydropyridine synthesis through a formal [3+2+1] fashion (up to 95 % yield, up to 99 % e.e.).","journal":"Angewandte Chemie International Edition","year":2023,"id":347770,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9418,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":867275,"name":"Yang‐Yang Xing","orcid":"0000-0001-6656-3293","position":1,"is_corresponding":false},{"id":267205,"name":"Xiaohan Ye","orcid":"0000-0002-3836-4120","position":2,"is_corresponding":false},{"id":1089633,"name":"Bao N. Nguyen","orcid":"0000-0002-0254-025X","position":3,"is_corresponding":false},{"id":369272,"name":"Łukasz Wojtas","orcid":"0000-0003-0545-0302","position":4,"is_corresponding":false},{"id":639232,"name":"Xin Hong","orcid":"0000-0003-4717-2814","position":5,"is_corresponding":false},{"id":267206,"name":"Xiaodong Shi","orcid":"0000-0002-3189-1315","position":6,"is_corresponding":false},{"id":472684,"name":"Jingwen Wei","orcid":"0000-0002-7286-0064","position":0,"is_corresponding":true}],"reference_count":72,"raw_metadata":null,"created_at":"2026-07-19T01:12:01.859977Z","pmid":"37167070","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}